ArticleThe Journal of comparative neurology2017
Congenital deafness affects deep layers in primary and secondary auditory cortex.
Article in The Journal of comparative neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Brain Morphological Modifications in Congenital and Acquired Auditory Deprivation: A Systematic Review and Coordinate-Based Meta-Analysis.Frontiers in neuroscience · 2022Pooled it
- Synaptic zinc plasticity shapes adaptive and maladaptive cortical plasticity following cochlear injury.Science advances · 2026Article
- Cytoarchitecture and myeloarchitecture of the sheep auditory cortex.Journal of anatomy · 2026Article
- Outcomes and prognostic factors in prelingually sensorineural deaf children with cerebral white matter lesions following cochlear implantation: a multicenter, retrospective study.Scientific reports · 2025Article
- Article
- Auditory areas are recruited for naturalistic visual meaning in early deaf people.Nature communications · 2024Article
- Cortical thickness differences between hearing and perinatally deaf cats using ultra-high field MRI.Neuroimage. Reports · 2024Article
- Multidimensional Alternating Kernel Method for cortical layer segmentation in 3D reconstructed histology.MethodsX · 2024Article
- Article
- The gradient in gray matter thickness across auditory cortex and differential cortical thickness changes following perinatal deafness.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Hearing and Cognition in Childhood.Laryngo- rhino- otologie · 2023Article
- Crossmodal plasticity in hearing loss.Trends in neurosciences · 2023Review
- Linking Cerebrovascular Dysfunction to Age-Related Hearing Loss and Alzheimer's Disease-Are Systemic Approaches for Diagnosis and Therapy Required?Biomolecules · 2022Review
- Somatosensory processing in deaf and deafblind individuals: How does the brain adapt as a function of sensory and linguistic experience? A critical review.Frontiers in psychology · 2022Review
- Deficient Recurrent Cortical Processing in Congenital Deafness.Frontiers in systems neuroscience · 2022Article
- Development of Auditory Cortex Circuits.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- Altered Functional Network in Infants With Profound Bilateral Congenital Sensorineural Hearing Loss: A Graph Theory Analysis.Frontiers in neuroscience · 2021Article
- Quantitative analyses of high-angular resolution diffusion imaging (HARDI)-derived long association fibers in children with sensorineural hearing loss.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2020Article
- Deafness Weakens Interareal Couplings in the Auditory Cortex.Frontiers in neuroscience · 2020Article
- Functional brain alterations following mild-to-moderate sensorineural hearing loss in children.eLife · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital deafness leads to functional deficits in the auditory cortex for which early cochlear implantation can effectively compensate. Most of these deficits have been demonstrated functionally. Furthermore, the majority of previous studies on deafness have involved the primary auditory cortex; knowledge of higher-order areas is limited to effects of cross-modal reorganization. In this study, we compared the cortical cytoarchitecture of four cortical areas in adult hearing and congenitally deaf cats (CDCs): the primary auditory field A1, two secondary auditory fields, namely the dorsal zone and second auditory field (A2); and a reference visual association field (area 7) in the same section stained either using Nissl or SMI-32 antibodies. The general cytoarchitectonic pattern and the area-specific characteristics in the auditory cortex remained unchanged in animals with congenital deafness. Whereas area 7 did not differ between the groups investigated, all auditory fields were slightly thinner in CDCs, this being caused by reduced thickness of layers IV-VI. The study documents that, while the cytoarchitectonic patterns are in general independent of sensory experience, reduced layer thickness is observed in both primary and higher-order auditory fields in layer IV and infragranular layers. The study demonstrates differences in effects of congenital deafness between supragranular and other cortical layers, but similar dystrophic effects in all investigated auditory fields.
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Registered trials
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