SynthesisPituitary2017
Visual outcomes after endoscopic endonasal pituitary adenoma resection: a systematic review and meta-analysis.
Synthesis in Pituitary, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Improved visual outcomes after endoscopic endonasal transsphenoidal surgery for pituitary macroadenomas: a single-arm meta-analysis.Acta neurochirurgica · 2026Pooled it
- Systematic review and network meta-analysis assess the comparative efficacy and safety of transsphenoidal surgery for pituitary tumor.Neurosurgical review · 2021Pooled it
- Article
- Characterization of the secretory profile of gonadotroph pituitary tumors.Journal of endocrinological investigation · 2026Article
- Preoperative radiological compression features and their relationship with pre- and postoperative visual field defects in pituitary macroadenomas: a retrospective cohort from the neuro-ophthalmological clinic.Frontiers in ophthalmology · 2026Article
- Post-operative Outcomes of Pituitary Macroadenoma Patients in a Tertiary Hospital in the Philippines.Journal of the ASEAN Federation of Endocrine Societies · 2025Article
- Risk factors and prognosis of visual and cranial nerve deficits in patients operated for pituitary tumor - with a focus on intrasellar pressure.Acta neurochirurgica · 2025Article
- Pituitary and Optic Tract Lesions Masquerading As Glaucoma: Highlighting Diagnostic Challenges.Cureus · 2025Article
- A core outcome set for pituitary surgery research: an international delphi consensus study.Pituitary · 2025Article
- Systematic review of fluorescence-guided surgery in pituitary neuroendocrine tumours.Endocrine oncology (Bristol, England) · 2025Review
- Optical coherence tomography in preoperative workup and visual outcome of pituitary macroadenomas.Surgical neurology international · 2025Article
- Artificial intelligence-driven approaches in pituitary neuroendocrine tumors: integrating endocrine-metabolic profiling for enhanced diagnostics and therapeutics.Frontiers in endocrinology · 2025Review
- Article
- Evaluating optic system compression in sellar tumors: A novel application of quantitative pupillometry.Acta neurochirurgica · 2024Article
- The Impact of Surgical Telementoring on Reducing the Complication Rate in Endoscopic Endonasal Surgery of the Skull Base.Diagnostics (Basel, Switzerland) · 2024Article
- Visual Pathway Recovery Post Pituitary Adenoma Surgery: Insights from Retinal Structure, Vascular Density, and Neural Conduction Analysis.Ophthalmology and therapy · 2024Article
- Multidisciplinary Team Care in Pituitary Tumours.Cancers · 2024Review
- Is the OCT a predictive tool to assess visual impairment in optic chiasm compressing syndrome in pituitary macroadenoma? A prospective longitudinal study.Neurosurgical review · 2024Observational
- Case Report: Atypical visual presentation caused by a large convexity meningioma-a nerve stretching and stalk indentation effect.Frontiers in surgery · 2024Article
- Surgical management of pituitary adenoma during pregnancy.World journal of clinical cases · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePatients with pituitary adenomas often present with visual deficits. While the aim of endoscopic endonasal transsphenoidal surgery (EETS) is to improve these deficits, permanent worsening is a possible outcome. The aim of this meta-analysis was to evaluate the effect of EETS for pituitary adenomas on visual outcomes.
methodsA meta-analysis was conducted according to the PRISMA guidelines. Pooled prevalence was calculated for complete recovery, improvement, and deterioration of visual field deficits, visual acuity and unspecified visual function in fixed- and random-effect models, including assessment of heterogeneity (I
resultsOut of 2636 articles, 35 case series were included in the meta-analysis. Results are described for fixed-effect models. For patients with impaired visual acuity, only one study reported complete recovery (27.2%). Pooled prevalence for improvement was 67.5% (95% CI = 59.1-75.0%), but with considerable heterogeneity (I
conclusionWhile visual deficits improved after EETS in the majority of patients, complete recovery was only achieved in less than half of the patients and some patients even suffered from visual deterioration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.