ArticleClinical and experimental nephrology2018
The incidence of the nephrotic syndrome in childhood in Germany.
Article in Clinical and experimental nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Estimation of childhood nephrotic syndrome incidence: data from the atlanta metropolitan statistical area and meta-analysis of worldwide cases.Journal of nephrology · 2022Pooled it
- Steroid treatment for the first episode of childhood nephrotic syndrome: comparison of the 8 and 12 weeks regimen using an individual patient data meta-analysis.European journal of pediatrics · 2021Pooled it
- Efficacy and safety of levamisole in childhood nephrotic syndrome: A meta-analysis.Indian journal of pharmacologyPooled it
- Clinical pattern of nephrotic syndrome and treatment response in children.Bioinformation · 2025Article
- Bioelectrical impedance vector analysis and phase angle to verify early hydration status and prognosis in hospitalized children with nephrotic syndrome: an exploratory case series.Frontiers in nutrition · 2025Article
- Incidence and Pathological Patterns of Nephrotic Syndrome among Infants and Children: A Systematic Review.Cureus · 2024Review
- Research on Rare Diseases in Germany - Using small fish and super-resolution microscopy to track down a rare disease.Journal of health monitoring · 2023Article
- Comparison of three spot proteinuria measurements for pediatric nephrotic syndrome: based on the International pediatric Nephrology Association 2022 Guidelines.Renal failure · 2023Article
- Kidney disease profile and encountered problems during follow-up in Syrian refugee children: a multicenter retrospective study.Pediatric nephrology (Berlin, Germany) · 2022Article
- KIAA0101 and IL2RA Were Identified as Core Genes in Hormone-Resistant Nephropathy.Disease markers · 2022Article
- Current understandings in treating children with steroid-resistant nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2021Review
- Association of low birth weight and prematurity with clinical outcomes of childhood nephrotic syndrome: a prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2019Article
- The long-term outcome of childhood nephrotic syndrome in Germany: a cross-sectional study.Clinical and experimental nephrology · 2019Article
- Clinical course & management of childhood nephrotic syndrome in Germany: a large epidemiological ESPED study.BMC nephrology · 2019Article
- Respiratory Tract Infection: A Risk Factor for the Onset and Relapse of Adult-Onset Minimal Change Disease in Southern China.BioMed research international · 2018Article
- Can microRNA profiles predict corticosteroid responsiveness in childhood nephrotic syndrome? A study protocol.BMJ paediatrics open · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of childhood nephrotic syndrome (NS) in Germany is not well known.
methodsAn ESPED-based nationwide collection of epidemiological data of children in 2005 and 2006.
resultThe mean age of NS at onset was 5.5 ± 3.7 years. The gender ratio of boys to girls was 1.8:1. The average length of stay was 15.5 ± 11.2 days, with younger children remaining significantly longer in hospital. Steroid-resistance was more common in children ≥8 years (p = 0.023). Focal-segmental glomerulosclerosis (FSGS) was more common in children >10 years (p = 0.029). The ratio of males to females with FSGS was 1:1.9, thus the FSGS risk for girls at onset was 3.3-times greater. Considering the available data, the incidence of NS in Germany is 1.2/100,000 in the population <18 years, of which 1.0/100,000 are steroid-sensitive.
conclusionCompared with international data, which primarily focused on regional and small populations, this is the largest study about the incidence of the childhood NS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.