ArticleEcoHealth2017
Burrow Dusting or Oral Vaccination Prevents Plague-Associated Prairie Dog Colony Collapse.
Article in EcoHealth, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 57 citations in OpenAlex.
- Trial
- From protection to amplification: Imperfect chytridiomycosis prophylaxis increases infections in wild amphibians.bioRxiv : the preprint server for biology · 2026Article
- Edible baits for systemic flea control, plague mitigation, and wildlife conservation: evaluation of four active ingredients with three rodent species in western North America.International journal for parasitology. Parasites and wildlife · 2026Article
- Article
- Den Use Patterns of Endangered San Joaquin Kit Foxes in Urban Environments May Facilitate Disease Transmission.Animals : an open access journal from MDPI · 2025Article
- Assessing potential collateral effects on amphibians from insecticide applications for flea control and plague mitigation.PloS one · 2025Article
- Prairie dog responses to vector control and vaccination during an initialInternational journal for parasitology. Parasites and wildlife · 2024Article
- Selection of an anti-pathogen skin microbiome following prophylaxis treatment in an amphibian model system.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Plague mitigation for prairie dog and black-footed ferret conservation: Degree and duration of flea control with 0.005% fipronil grain bait.Current research in parasitology & vector-borne diseases · 2023Article
- Potential Effects of Environmental Conditions on Prairie Dog Flea Development and Implications for Sylvatic Plague Epizootics.EcoHealth · 2022Article
- Reevaluation of the Role of Blocked Oropsylla hirsuta Prairie Dog Fleas (Siphonaptera: Ceratophyllidae) in Yersinia pestis (Enterobacterales: Enterobacteriaceae) Transmission.Journal of medical entomology · 2022Article
- Exploring and Mitigating Plague for One Health Purposes.Current tropical medicine reports · 2022Article
- Oral Sylvatic Plague Vaccine Does Not Adequately Protect Prairie Dogs (Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2021Article
- No evidence for enzootic plague within black-tailed prairie dog (Cynomys ludovicianus) populations.Integrative zoology · 2021Article
- Asymmetric cross-strain protection for amphibians exposed to a fungal-metabolite prophylactic treatment.Biology letters · 2021Article
- Plague vaccines: new developments in an ongoing search.Applied microbiology and biotechnology · 2021Review
- Plague transforms positive effects of precipitation on prairie dogs to negative effects.International journal for parasitology. Parasites and wildlife · 2021Article
- Article
- An invasive disease, sylvatic plague, increases fragmentation of black-tailed prairie dog (Cynomys ludovicianus) colonies.PloS one · 2020Article
- Intestinal B cells in the red-eared slider turtle, Trachemys scripta: Anatomical distribution and implications for ecological interactions with pathogenic microbes.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plague impacts prairie dogs (Cynomys spp.), the endangered black-footed ferret (Mustela nigripes) and other sensitive wildlife species. We compared efficacy of prophylactic treatments (burrow dusting with deltamethrin or oral vaccination with recombinant "sylvatic plague vaccine" [RCN-F1/V307]) to placebo treatment in black-tailed prairie dog (C. ludovicianus) colonies. Between 2013 and 2015, we measured prairie dog apparent survival, burrow activity and flea abundance on triplicate plots ("blocks") receiving dust, vaccine or placebo treatment. Epizootic plague affected all three blocks but emerged asynchronously. Dust plots had fewer fleas per burrow (P < 0.0001), and prairie dogs captured on dust plots had fewer fleas (P < 0.0001) than those on vaccine or placebo plots. Burrow activity and prairie dog density declined sharply in placebo plots when epizootic plague emerged. Patterns in corresponding dust and vaccine plots were less consistent and appeared strongly influenced by timing of treatment applications relative to plague emergence. Deltamethrin or oral vaccination enhanced apparent survival within two blocks. Applying insecticide or vaccine prior to epizootic emergence blunted effects of plague on prairie dog survival and abundance, thereby preventing colony collapse. Successful plague mitigation will likely entail strategic combined uses of burrow dusting and oral vaccination within large colonies or colony complexes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.