Evidence map›Paper›PMID 28643049›Full record

ReviewThe Psychiatric quarterly2018

Clozapine in Reducing Aggression and Violence in Forensic Populations.

Kathleen Patchan, Gopal Vyas, Ann L Hackman, Marie Mackowick, Charles M Richardson, Raymond C Love, Ikwunga Wonodi, MacKenzie A Sayer, Matthew Glassman, Stephanie Feldman and 1 more

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Psychiatric quarterly, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kathleen PatchanDepartment of Psychiatry, University of Maryland School of Medicine, 630 W Fayette St, Baltimore, MD, 21201, USA.
Gopal VyasSpring Grove Hospital and Maryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.
Ann L HackmanDepartment of Psychiatry, University of Maryland School of Medicine, 630 W Fayette St, Baltimore, MD, 21201, USA.
Marie MackowickClifton T. Perkins Hospital Center, 8450 Dorsey Run Rd, Jessup, MD, 20794, USA.
Charles M RichardsonSpring Grove Hospital and Maryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.
Raymond C LoveSchool of Pharmacy, University of Maryland, 20 N Pine St, Baltimore, MD, 21201, USA.
Ikwunga WonodiMaryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.
MacKenzie A SayerMaryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.
Matthew GlassmanMaryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.
Stephanie FeldmanMaryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA.
Deanna L KellyMaryland Psychiatric Research Center, University of Maryland School of Medicine, PO Box 21247, Baltimore, MD, 21228, USA. dkelly@mprc.umaryland.edu.
University of Maryland, Baltimore · USClifton T. Perkins Hospital Center · US

Funding

Biomarker and Safety Study of Clozapine in Benign Ethnic NeutropeniaR01MH102215 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI KELLY, DEANNA L · 2015 to 2018
$3.4M
Microsystem Development for Clozapine Monitoring in SchizophreniaR56MH105571 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI GHODSSI, REZA, KELLY, DEANNA L · 2015 to 2016
$741k
NIMH NIH HHS R01 MH102215NIMH NIH HHS R01 MH105571-01NIMH NIH HHS R56 MH105571
6 · The paper itself

Abstract

Popular media often portray people with a mental illness as being aggressive, violent, and incarcerated as a result of their behavior. Despite exaggeration in the media, risks for some aggressive behaviors are in fact higher in individuals with schizophrenia. This is often the case with influence of comorbid substance use disorders. It is essential that mental health professionals are aware of treatments that may help with attenuating and treating behaviors that contribute to violence, aggression and incarceration. This paper reviews violence and incarceration in individuals with schizophrenia as well as recommendations, guidelines and benefits for the use of clozapine in this population. Clozapine remains one of the most underutilized evidence-based medications available in the psychiatric arena in the United States. It is a viable and recommended option in the forensic population and it may be helpful on the path to recovery as well as bring substantial savings to the criminal justice system.

Indexed as

Criminal LawCriminalsAggressionAntipsychotic AgentsClozapineHumansSchizophreniaViolenceAntipsychotic AgentsClozapineAggressionClozapineCriminal justiceForensicViolence

Identifiers

PMID28643049
PMCPMC5930356
OpenAlexW2674096101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.