Evidence map›Paper›PMID 28643045›Full record

ArticleLasers in medical science2017

Validation of a mathematical model for laser-induced thermotherapy in liver tissue.

F Hübner, C Leithäuser, B Bazrafshan, N Siedow, T J Vogl

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 23 citations in OpenAlex.

  1. Modeling andFrontiers in neurology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

F HübnerInstitut für Diagnostische und Interventionelle Radiologie, Theodor-Stern-Kai 7, Haus 23c, 60590, Frankfurt, Germany. frank.huebner@kgu.de.
C LeithäuserFraunhofer Institut für Techno- und Wirtschaftsmathematik (ITWM), Fraunhofer-Platz 1, 67663, Kaiserslautern, Germany.
B BazrafshanInstitut für Diagnostische und Interventionelle Radiologie, Theodor-Stern-Kai 7, Haus 23c, 60590, Frankfurt, Germany.
N SiedowFraunhofer Institut für Techno- und Wirtschaftsmathematik (ITWM), Fraunhofer-Platz 1, 67663, Kaiserslautern, Germany.
T J VoglInstitut für Diagnostische und Interventionelle Radiologie, Theodor-Stern-Kai 7, Haus 23c, 60590, Frankfurt, Germany.
Fraunhofer Institute for Industrial Mathematics · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of the study was to develop a simulation approach for laser-induced thermotherapy (LITT) that is based on mathematical models for radiation transport, heat transport, and tissue damage. The LITT ablation was applied to ex vivo pig liver tissue. Experiments were repeated with different laser powers, i.e., 22-34 W, and flow rates of the cooling water in the applicator system, i.e., 47-92 ml/min. During the procedure, the temperature was measured in the liver sample at different distances to the applicator as well as in the cooling circuit using a fiber optic thermometer. For validation, the simulation results were compared with the results of the laser ablation experiments in the ex vivo pig liver samples. The simulated and measured temperature curves presented a relatively good agreement. The Bland-Altman plot showed an average of temperature differences of -0.13

Indexed as

LasersModels, TheoreticalAnimalsHyperthermia, InducedLiverSus scrofaTemperatureThermometersBio-heat equationLITTLiver tissueRadiative transferSimulationTumor ablation

Identifiers

PMID28643045
OpenAlexW2703035483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.