Evidence map›Paper›PMID 28642843›Full record

ArticleFrontiers in cellular and infection microbiology2017

The Impact of Genome Region of Difference 4 (RD4) on Mycobacterial Virulence and BCG Efficacy.

Huanwei Ru, Xiaojia Liu, Chen Lin, Jingyan Yang, Fuzeng Chen, Ruifeng Sun, Lu Zhang, Jun Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Genetic diversity and antibiotic resistance ofFrontiers in cellular and infection microbiology · 2025
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  5. Genetic diversities ofAccess microbiology · 2024
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  9. Effects ofAnnals of translational medicine · 2022
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  10. Frontiers in immunology · 2022
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  11. Insights into the ancestry evolution of theNAR genomics and bioinformatics · 2021
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  12. Article
  13. Pan and Core Genome Analysis of 183Antibiotics (Basel, Switzerland) · 2021
    Article
  14. Review
  15. ImmunodominantFrontiers in immunology · 2020
    Article
  16. Article
  17. Pan-Genomic Study ofFrontiers in microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Huanwei RuState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Xiaojia LiuState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Chen LinState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Jingyan YangState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Fuzeng ChenState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Ruifeng SunState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Lu ZhangState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Jun LiuState Key Laboratory of Genetic Engineering, School of Life Science, Institute of Genetics, Fudan UniversityShanghai, China.
Fudan University · CNState Key Laboratory of Genetic Engineering

Funding

CIHR MOP-106559
6 · The paper itself

Abstract

Comparative genome analyses have revealed a number of regions of difference (RD) among mycobacterial species. The functional consequences of most of these genome variations have not been studied. RD4, which encompasses Rv1506c-Rv1516c of

Indexed as

Genes, BacterialAnimalsBacterial ProteinsBCG VaccineCell LineCloning, MolecularDisease Models, AnimalDNA, BacterialGene DeletionImmunizationMiceMice, SCIDMycobacterium bovisMycobacterium marinumMycobacterium tuberculosisTuberculosisBacterial ProteinsBCG VaccineDNA, BacterialTuberculosis VaccinesVaccines, AttenuatedVaccines, SyntheticbacterialgenomeMycobacterium bovis BCGMycobacterium marinumMycobacterium tuberculosisRD4

Identifiers

PMID28642843
PMCPMC5462905
OpenAlexW2622762731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.