Evidence map›Paper›PMID 28642840›Full record

ArticleFrontiers in cellular and infection microbiology2017

Cytolethal Distending Toxin Enhances Radiosensitivity in Prostate Cancer Cells by Regulating Autophagy.

Hwai-Jeng Lin, Hsin-Ho Liu, Chia-Der Lin, Min-Chuan Kao, Yu-An Chen, Chuan Chiang-Ni, Zhi-Pei Jiang, Mei-Zi Huang, Chun-Jung Lin, U-Ging Lo and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Hwai-Jeng LinDivision of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical UniversityTaipei, Taiwan.
Hsin-Ho LiuDivision of Urology, Department of Surgery, Taichung Tzu Chi General HospitalTaichung, Taiwan.
Chia-Der LinDepartment of Otolaryngology-Head and Neck Surgery, China Medical University and HospitalTaichung, Taiwan.
Min-Chuan KaoDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung UniversityTaoyuan, Taiwan.
Yu-An ChenDepartment of Medical Research, School of Medicine, Graduate Institute of Basic Medical Sciences, China Medical University and HospitalTaichung, Taiwan.
Chuan Chiang-NiDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung UniversityTaoyuan, Taiwan.
Zhi-Pei JiangDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung UniversityTaoyuan, Taiwan.
Mei-Zi HuangDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung UniversityTaoyuan, Taiwan.
Chun-Jung LinDepartment of Urology, University of Texas Southwestern Medical CenterDallas, TX, United States.
U-Ging LoDepartment of Urology, University of Texas Southwestern Medical CenterDallas, TX, United States.
Li-Chiung LinDepartment of Urology, University of Texas Southwestern Medical CenterDallas, TX, United States.
Cheng-Kuo LaiDepartment of Life Sciences, National Chung Hsing UniversityTaichung, Taiwan.
Ho LinDepartment of Life Sciences, National Chung Hsing UniversityTaichung, Taiwan.
Jer-Tsong HsiehDepartment of Urology, University of Texas Southwestern Medical CenterDallas, TX, United States.
Cheng-Hsun ChiuDepartment of Pediatrics, Molecular Infectious Disease Research Center, Chang Gung Children's Hospital and Chang Gung Memorial HospitalTaoyuan, Taiwan.
Chih-Ho LaiDepartment of Medical Research, School of Medicine, Graduate Institute of Basic Medical Sciences, China Medical University and HospitalTaichung, Taiwan.
Chang Gung University of Science and Technology · TWNational Chung Hsing University · TWChang Gung University · TWAsia University · TWChina Medical University · TWNational Taiwan University · TWSouthwestern Medical Center · US

Funding

Developing targeted therapy with prostate cancer specific nanomedicineR01CA182670 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI HSIEH, JER-TSONG, YANG, JIAN · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA182670
6 · The paper itself

Abstract

Cytolethal distending toxin (CDT) produced by

Indexed as

AnimalsApoptosisAutophagosomesAutophagyBacterial ToxinsCampylobacter jejuniCell CycleCell Cycle CheckpointsCell LineDrug Therapy, CombinationHMGB1 ProteinHumansMaleMiceProstateProstatic NeoplasmsBacterial Toxinscytolethal distending toxinHMGB1 ProteinautophagyCampylobacter jejunicell cyclecytolethal distending toxinradioresistance

Identifiers

PMID28642840
PMCPMC5462984
OpenAlexW2622160398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.