Evidence map›Paper›PMID 28642835›Full record

ArticleNagoya Gakuin Daigaku ronshu. Igaku, kenko kagaku, supotsu kagakuhen2017

Differential Carbonyl Stress Expression in the Intervertebral Disc between Singular- and Persistent-Mechanical Injuries.

Itaru Hibino, Simon Tang

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Nagoya Gakuin Daigaku ronshu. Igaku, kenko kagaku, supotsu kagakuhen, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Itaru HibinoDepartment of Physical Therapy, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, Aichi, JAPAN.
Simon TangDepartment of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, MO.
Washington University in St. Louis · US

Funding

The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI VEIS, DEBORAH J · 2009 to 2018
$5.7M
Development of Bioengineered Skeletal Muscle for Functional Replacement in vivoR01AR057325 · NIAMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHRIST, GEORGE JOSEPH · 2009 to 2010
$740k
Tissue Level Deformations of the Loaded Spine in Humans with Low Back PainK01AR069116 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2016 to 2019
$489k
Effects of Ages and Rage on IVD Degeneration And InflammationR21AR069804 · NIAMS · WASHINGTON UNIVERSITY · PI TANG, SIMON YUE-CHEONG · 2017 to 2018
$369k
NIAMS NIH HHS K01 AR069116NIAMS NIH HHS P30 AR057235NIAMS NIH HHS R01 AR057325NIAMS NIH HHS R21 AR069804
6 · The paper itself

Abstract

Low back pain is a significant public health problem worldwide. Intervertebral disc degeneration is most significant known risk factor for low back pain. Yet the mechanisms of degeneration remain relatively unknown. Carbonyl stress and oxidation have been implicated in cartilage and fibrocartilage degeneration. Here we investigate the role of oxidative stress and carbonyl production in the intervertebral disc after mechanical injury using an

Indexed as

Carbonyl stressIntervertebral disc degenerationLow back painMechanical injury

Identifiers

PMID28642835
PMCPMC5477789
OpenAlexW2751100352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.