Evidence map›Paper›PMID 28642810›Full record

Trial reportOxidative medicine and cellular longevity2017

Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes.

David B Bartlett, Cris A Slentz, Margery A Connelly, Lucy W Piner, Leslie H Willis, Lori A Bateman, Esther O Granville, Connie W Bales, Kim M Huffman, William E Kraus

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Title: Human Serum/Plasma Glycoprotein Analysis byJournal of clinical medicine · 2020
    Review
  14. Article
  15. Observational
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David B BartlettDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.ORCID 0000-0001-7838-898X
Cris A SlentzDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Margery A ConnellyLipoScience, Laboratory Corporation of America Holdings, Morrisville, NC, USA.
Lucy W PinerDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Leslie H WillisDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Lori A BatemanDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Esther O GranvilleDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Connie W BalesDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
Kim M HuffmanDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
William E KrausDuke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.

Funding

Exercise Dose-Response Effects in Prediabetes:Responses and MechanismsR01DK081559 · NIDDK · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 2009 to 2013
$3.1M
NIDDK NIH HHS R01 DK081559
6 · The paper itself

Abstract

GlycA is a new composite measure of systemic inflammation and a predictor of many inflammatory diseases. GlycA is the nuclear magnetic resonance spectroscopy-derived signal arising from glucosamine residues on acute-phase proteins. This study aimed to evaluate how exercise-based lifestyle interventions modulate GlycA in persons at risk for type 2 diabetes. GlycA, fitness, and body habitus were measured in 169 sedentary adults (45-75 years) with prediabetes randomly assigned to one of four six-month exercise-based lifestyle interventions. Interventions included exercise prescription based on the amount (energy expenditure (kcal/kg weight/week (KKW)) and intensity (%VO

Indexed as

AgedBiomarkersBody WeightExerciseFemaleHumansInflammationMaleMiddle AgedPrediabetic StateBiomarkers

Identifiers

PMID28642810
PMCPMC5470023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.