ArticleActa ortopedica brasileira
ROLE OF DIFFERENT HORMONES IN THE PATHOGENESIS AND SEVERITY OF ADOLESCENT IDIOPATHIC SCOLIOSIS.
Article in Acta ortopedica brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Vitamin-D status in sixty adolescents with idiopathic scoliosis: An observational study.Pakistan journal of medical sciences · 2026Article
- Review
- EEG Microstate as a Marker of Adolescent Idiopathic Scoliosis.IEEE open journal of engineering in medicine and biology · 2024Article
- Back pain in adolescent idiopathic scoliosis: A comprehensive review.Journal of children's orthopaedics · 2023Review
- Brain oscillatory activity in adolescent idiopathic scoliosis.Scientific reports · 2022Article
- Controlling the Progression of Curvature in Children and Adolescent Idiopathic Scoliosis Following the Administration of Melatonin, Calcium, and Vitamin D.Children (Basel, Switzerland) · 2022Article
- Salivary Progesterone Levels in Female Patients with a History of Idiopathic Scoliosis: A Retrospective Cross-Sectional Study.Clinics and practice · 2022Article
- 3D Deformation Patterns of S Shaped Elastic Rods as a Pathogenesis Model for Spinal Deformity in Adolescent Idiopathic Scoliosis.Scientific reports · 2019Article
- Pitfalls with Vitamin D Research in Musculoskeletal Disorders and Recommendations on How to Avoid ThemJournal of clinical research in pediatric endocrinology · 2019Review
- The Role of Vitamin D in the Pathogenesis of Adolescent Idiopathic Scoliosis.Asian spine journal · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the hormonal profile of patients with adolescent idiopathic scoliosis (AIS) and its relationship to the severity of the curvature and quality of life
methodPatients with scoliosis (Cobb angle above 10°), of both genders, diagnosed after 10 years of age were included, excluding those who presented other condition that could lead to scoliosis. Serum levels of 25-hydroxyvitamin D (25-OHD), cortisol and gastrin were correlated with Cobb angle and quality of life, measured by the SRS-30 questionnaire
resultsThe levels of 25-OHD decreased in 97% of patients. There was an inverse relationship between gastrin levels and quality of life (p = 0.016). Moreover, there was an inverse correlation between the value of Cobb angle and quality of life (p = 0.036). There were no changes in cortisol levels. There was no correlation between Cobb angle and any of the hormones measured
conclusionThe patients had levels of 25-OHD diminished, strengthening the hypothesis of its involvement in the development of AIS. This study also suggests that increased gastrin levels may be associated with a worse quality of life in patients with AIS.
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