Evidence map›Paper›PMID 28642629›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2017

Improved brain tumor segmentation by utilizing tumor growth model in longitudinal brain MRI.

Linmin Pei, Syed M S Reza, Wei Li, Christos Davatzikos, Khan M Iftekharuddin

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linmin PeiVision Lab, Electrical & Computer Engineering, Old Dominion University.
Syed M S RezaVision Lab, Electrical & Computer Engineering, Old Dominion University.
Wei LiDepartment of Mathematics & Statistics, Old Dominion University.
Christos DavatzikosDepartment of Radiology, University of Pennsylvania, Philadelphia, PA.
Khan M IftekharuddinVision Lab, Electrical & Computer Engineering, Old Dominion University.

Funding

Quantitative imaging and molecular data modeling for brain tumor recurrence and progression analysisR01EB020683 · NIBIB · OLD DOMINION UNIVERSITY · PI Khan M Iftekharuddin · 2016 to 2026
$3.2M
Multiresolution-fractal modeling for brain tumor detectionR15CA115464 · NCI · UNIVERSITY OF MEMPHIS · PI IFTEKHARUDDIN, KHAN M · 2010 to 2010
$473k
NCI NIH HHS R15 CA115464NIBIB NIH HHS R01 EB020683
6 · The paper itself

Abstract

In this work, we propose a novel method to improve texture based tumor segmentation by fusing cell density patterns that are generated from tumor growth modeling. In order to model tumor growth, we solve the reaction-diffusion equation by using Lattice-Boltzmann method (LBM). Computational tumor growth modeling obtains the cell density distribution that potentially indicates the predicted tissue locations in the brain over time. The density patterns is then considered as novel features along with other texture (such as fractal, and multifractal Brownian motion (mBm)), and intensity features in MRI for improved brain tumor segmentation. We evaluate the proposed method with about one hundred longitudinal MRI scans from five patients obtained from public BRATS 2015 data set, validated by the ground truth. The result shows significant improvement of complete tumor segmentation using ANOVA analysis for five patients in longitudinal MR images.

Indexed as

cell densityLattice-Boltzmann methodlongitudinal MRIreaction-diffusion equationtumor growth modelTumor segmentation

Identifiers

PMID28642629
PMCPMC5476314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.