Evidence map›Paper›PMID 28642474›Full record

ArticleScientific reports2017

Comparing DNA enrichment of proliferating cells following administration of different stable isotopes of heavy water.

Don E Farthing, Nataliya P Buxbaum, Philip J Lucas, Natella Maglakelidze, Brittany Oliver, Jiun Wang, Kevin Hu, Ehydel Castro, Catherine V Bare, Ronald E Gress

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

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  4. Active involvement of compartmental, inter- and intramolecular deuterium disequilibrium in adaptive biology.Proceedings of the National Academy of Sciences of the United States of America · 2024
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  14. TheScientificWorldJournal · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Don E FarthingNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States. farthingde@mail.nih.gov.
Nataliya P BuxbaumNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Philip J LucasNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Natella MaglakelidzeNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Brittany OliverOCRT&ME, 10 Center Drive, Bethesda, MD, 20814, United States.
Jiun WangNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Kevin HuNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Ehydel CastroNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Catherine V BareNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
Ronald E GressNational Institutes of Health (NIH), National Cancer Institute (NCI), Experimental Transplantation and Immunology (ETIB), 10 Center Drive, Bethesda, MD, 20892, United States.
National Cancer Institute · USNational Institutes of Health · US

Funding

Immune ReconstitutionZIABC010525 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI GRESS, RONALD · 2009 to 2023
$21.9M
Stable Water Isotope Labeling for Imaging of Rapidly Proliferating CellsZIABC011777 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BUXBAUM, NATALIYA · 2017 to 2021
$481k
6 · The paper itself

Abstract

Deuterated water (

Indexed as

Isotope LabelingAnimalsCell Line, TumorCell ProliferationDeuterium OxideDNADNA ReplicationMass SpectrometryMiceDeuterium OxideDNA

Identifiers

PMID28642474
PMCPMC5481421
OpenAlexW2625364300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.