Evidence map›Paper›PMID 28642277›Full record

ArticleJournal of leukocyte biology2017

Adipose tissue macrophages develop from bone marrow-independent progenitors in

Syed F Hassnain Waqas, Anna Noble, Anh C Hoang, Grace Ampem, Manuela Popp, Sarah Strauß, Matthew Guille, Tamás Röszer

Open access · hybridAbstract read
In one paragraph

Article in Journal of leukocyte biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 75 citations in OpenAlex.

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  14. Macrophage and T cell networks in adipose tissue.Nature reviews. Endocrinology · 2024
    Review
  15. Article
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  18. Biology · 2023
    Review
  19. Review
  20. Adipose tissue metabolic changes in chronic kidney disease.Immunometabolism (Cobham, Surrey) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Syed F Hassnain WaqasInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
Anna NobleEuropean Xenopus Resource Centre, School of Biological Sciences, University of Portsmouth, Portsmouth, United Kingdom.
Anh C HoangInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
Grace AmpemInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
Manuela PoppInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.
Sarah StraußAmbystoma Mexicanum Bioregeneration Center, Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hannover Medical School, Medizinische Hochschule Hannover, Hannover, Germany.
Matthew GuilleEuropean Xenopus Resource Centre, School of Biological Sciences, University of Portsmouth, Portsmouth, United Kingdom.
Tamás RöszerInstitute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany; tamas.roeszer@uni-ulm.de.
Universität Ulm · DEUniversity of Portsmouth · GBMedizinische Hochschule Hannover · DE

Funding

Wellcome Trust
6 · The paper itself

Abstract

ATMs have a metabolic impact in mammals as they contribute to metabolically harmful AT inflammation. The control of the ATM number may have therapeutic potential; however, information on ATM ontogeny is scarce. Whereas it is thought that ATMs develop from circulating monocytes, various tissue-resident Mϕs are capable of self-renewal and develop from BM-independent progenitors without a monocyte intermediate. Here, we show that amphibian AT contains self-renewing ATMs that populate the AT before the establishment of BM hematopoiesis.

Indexed as

Adipose TissueMacrophagesStem CellsAnimalsBone Marrow CellsCell DifferentiationMiceXenopus laevisCX3CR1fat bodyneuropeptide FFyolk sac Mϕs

Identifiers

PMID28642277
PMCPMC5574031
OpenAlexW2713158710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.