Evidence map›Paper›PMID 28642265›Full record

ArticleAJNR. American journal of neuroradiology2017

The Initial Area Under the Curve Derived from Dynamic Contrast-Enhanced MRI Improves Prognosis Prediction in Glioblastoma with Unmethylated

Y S Choi, S S Ahn, H-J Lee, J H Chang, S-G Kang, E H Kim, S H Kim, S-K Lee

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Clinically Relevant Imaging Features forAJNR. American journal of neuroradiology · 2018
    Pooled it
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  11. Conventional and advanced magnetic resonance imaging in patients with high-grade glioma.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Y S ChoiFrom the Department of Radiology and Research Institute of Radiological Science (Y.S.C., S.S.A., H.-J.L., S.-K.L.).ORCID http://orcid.org/0000-0002-6034-9912
S S AhnFrom the Department of Radiology and Research Institute of Radiological Science (Y.S.C., S.S.A., H.-J.L., S.-K.L.).ORCID http://orcid.org/0000-0002-0503-5558
H-J LeeFrom the Department of Radiology and Research Institute of Radiological Science (Y.S.C., S.S.A., H.-J.L., S.-K.L.).ORCID http://orcid.org/0000-0003-0831-6184
J H ChangNeurosurgery (J.H.C., S.-G.K., E.H.K.), Yonsei University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0003-1509-9800
S-G KangNeurosurgery (J.H.C., S.-G.K., E.H.K.), Yonsei University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0001-5676-2037
E H KimNeurosurgery (J.H.C., S.-G.K., E.H.K.), Yonsei University College of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0002-2523-7122
S H KimDepartments of Pathology (S.H.K.).ORCID http://orcid.org/0000-0001-7516-7372
S-K LeeFrom the Department of Radiology and Research Institute of Radiological Science (Y.S.C., S.S.A., H.-J.L., S.-K.L.) SLEE@yuhs.ac.ORCID http://orcid.org/0000-0001-5646-4072
Research Institute of Radiology · BYYonsei University · KRNorwegian Womens Public Health Association · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeAlthough perfusion and permeability MR parameters have known to have prognostic value, they have reproducibility issues. Our aim was to evaluate whether the initial area under the time-to-signal intensity curve (IAUC) derived from dynamic contrast-enhanced MR imaging can improve prognosis prediction in patients with glioblastoma with known MATERIALS AND

methodsWe retrospectively examined 88 patients with glioblastoma who underwent preoperative dynamic contrast-enhanced MR imaging. The means of IAUC values at 30 and 60 seconds (IAUC30

resultsHigh IAUC parameters were associated with worse overall survival and progression-free survival in the unmethylated

conclusionsIAUC can be a useful prognostic imaging biomarker in patients with glioblastoma with known

Indexed as

AdultAgedArea Under CurveBrain NeoplasmsDisease-Free SurvivalDNA MethylationDNA Modification MethylasesDNA Repair EnzymesFemaleGlioblastomaHumansMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingPrognosisDNA Modification MethylasesDNA Repair EnzymesMGMT protein, humanTumor Suppressor Proteins

Identifiers

PMID28642265
PMCPMC7960440
OpenAlexW2688529656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.