Evidence map›Paper›PMID 28642070›Full record

ReviewNeuroscience and biobehavioral reviews2017

Conceptualising compensation in neurodevelopmental disorders: Reflections from autism spectrum disorder.

Lucy Anne Livingston, Francesca Happé

Abstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 186 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
186citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

186 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A comparison of methods for measuring camouflaging in autism.Autism research : official journal of the International Society for Autism Research · 2023
    Pooled it
  4. A Systematic Review of Passing as Non-autistic in Autism Spectrum Disorder.Clinical child and family psychology review · 2021
    Pooled it
  5. Pooled it
  6. Trial
  7. Article
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  12. Article
  13. Article
  14. Aberrant Neural Entrainment to Word-Level Speech Patterns in Fragile X Syndrome: Evidence for a Statistical Learning Deficit.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  15. Article
  16. Review
  17. The Cost of Social Integration: Distinct Neural Inefficiency in Autistic Children Underlies Symptom Severity.Autism research : official journal of the International Society for Autism Research · 2026
    Article
  18. Review
  19. Camouflaging and autism: Conceptualisation and methodological issues.Autism : the international journal of research and practice · 2026
    Review
  20. Article

126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lucy Anne LivingstonMRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK. Electronic address: lucy.livingston@kcl.ac.uk.
Francesca HappéMRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, SE5 8AF, UK. Electronic address: francesca.happe@kcl.ac.uk.

Funding

Medical Research Council G0500870
6 · The paper itself

Abstract

Within research into neurodevelopmental disorders, little is known about the mechanisms underpinning changes in symptom severity across development. When the behavioural presentation of a condition improves/symptoms lessen, this may be because core underlying atypicalities in cognition/neural function have ameliorated. An alternative possibility is 'compensation'; that the behavioural presentation appears improved, despite persisting deficits at cognitive and/or neurobiological levels. There is, however, currently no agreed technical definition of compensation or its behavioural, cognitive and neural characteristics. Furthermore, its workings in neurodevelopmental disorders have not been studied directly. Here, we review current evidence for compensation in neurodevelopmental disorders, using Autism Spectrum Disorder as an example, in order to move towards a better conceptualisation of the construct. We propose a transdiagnostic framework, where compensation represents the processes responsible for an observed mismatch between behaviour and underlying cognition in a neurodevelopmental disorder, at any point in development. Further, we explore potential cognitive and neural mechanisms driving compensation and discuss the broader relevance of the concept within research and clinical settings.

Indexed as

Concept FormationHumansModels, PsychologicalNeurodevelopmental DisordersAdaptationAutism Spectrum DisorderBehavioural phenotypeCamouflagingCognitive phenotypeCompensationCompensatory mechanismsExecutive functionFemale presentationGood outcomeLate diagnosisNeurodevelopmental disordersRemediationTheory of mindUnaffected siblingsUnder-diagnosis

Identifiers

PMID28642070
PMCPMC7374933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.