ArticleNeurobiology of aging2017
Genome-wide association and interaction studies of CSF T-tau/Aβ
Abstract read
In one paragraph
Article in Neurobiology of aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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18citing papers in PubMed, 2 pooled it
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Genetic Variability in Molecular Pathways Implicated in Alzheimer's Disease: A Comprehensive Review.Frontiers in aging neuroscience · 2021Pooled it
- Viral Induced Oxidative and Inflammatory Response in Alzheimer's Disease Pathogenesis with Identification of Potential Drug Candidates: A Systematic Review using Systems Biology Approach.Current neuropharmacology · 2019Pooled it
- Combating ageing beyond the cell: Emerging roles of extracellular proteostasis.The FEBS journal · 2026Review
- Identification of novel protective loci for executive function using the trail making test part B in the Long Life Family Study.bioRxiv : the preprint server for biology · 2025Article
- Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Genome-wide epistasis analysis reveals gene-gene interaction network on an intermediate endophenotype P-tau/AβScientific reports · 2024Article
- A review and analysis of key biomarkers in Alzheimer's disease.Frontiers in neuroscience · 2024Review
- Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer's disease.Brain : a journal of neurology · 2023Article
- Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's disease related proteins.Molecular neurodegeneration · 2023Article
- X chromosome-wide association study of quantitative biomarkers from the Alzheimer's Disease Neuroimaging Initiative study.Frontiers in aging neuroscience · 2023Article
- Predictive classification of Alzheimer's disease using brain imaging and genetic data.Scientific reports · 2022Article
- Morbigenous brain region and gene detection with a genetically evolved random neural network cluster approach in late mild cognitive impairment.Bioinformatics (Oxford, England) · 2020Article
- A Multicenter Preclinical MRI Study: Definition of Rat Brain Relaxometry Reference Maps.Frontiers in neuroinformatics · 2020Article
- Benchmarking machine learning models for late-onset alzheimer's disease prediction from genomic data.BMC bioinformatics · 2019Article
- Quantitative Trait Module-Based Genetic Analysis of Alzheimer's Disease.International journal of molecular sciences · 2019Article
- A Comprehensive Analysis of the CaMK2A Gene and Susceptibility to Alzheimer's Disease in the Han Chinese Population.Frontiers in aging neuroscience · 2019Article
- Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development.Frontiers in genetics · 2018Article
- Specific protein biomarker patterns for Alzheimer's disease: improved diagnostics in progress.The EPMA journal · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Jin LiCollege of Automation, Harbin Engineering University, Harbin, China.
Qiushi ZhangCollege of Automation, Harbin Engineering University, Harbin, China; College of Information Engineering, Northeast Dianli University, Jilin, China.
Feng ChenCollege of Automation, Harbin Engineering University, Harbin, China.
Xianglian MengCollege of Automation, Harbin Engineering University, Harbin, China.
Wenjie LiuCollege of Automation, Harbin Engineering University, Harbin, China.
Dandan ChenCollege of Automation, Harbin Engineering University, Harbin, China; College of Information Engineering, Northeast Dianli University, Jilin, China.
Jingwen YanCenter for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA; Department of BioHealth Informatics, Indiana University School of Informatics and Computing, Indianapolis, IN, USA.
Sungeun KimCenter for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
Lei WangCollege of Automation, Harbin Engineering University, Harbin, China.
Weixing FengCollege of Automation, Harbin Engineering University, Harbin, China.
Andrew J SaykinCenter for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA.
Hong LiangCollege of Automation, Harbin Engineering University, Harbin, China. Electronic address: lh@hrbeu.edu.cn.
Li ShenCenter for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN, USA; Department of BioHealth Informatics, Indiana University School of Informatics and Computing, Indianapolis, IN, USA. Electronic address: shenli@iu.edu.
Alzheimer's Disease Neuroimaging Initiative
Funding
Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI Paul S. Aisen · 2016 to 2026
$226.7MAlzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0MResearch Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3MAmyloid Imaging, VMCI, and Analysis for ADNIRC2AG036535 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI WEINER, MICHAEL W · 2009 to 2010
$23.8MIndiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3MMetabolomic Signatures for Disease Sub-classification and Target Prioritization in AMP-ADU01AG061359 · NIA · DUKE UNIVERSITY · PI KADDURAH-DAOUK, RIMA F, KASTENMULLER, GABI · 2018 to 2022
$10.0MMemory Circuitry in MCI and Early Alzheimer’s Disease Prodrome: Molecular DriversR01AG019771 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 2001 to 2021
$6.9MIntegrative Bioinformatics Approaches to Human Brain Genomics and ConnectomicsR01EB022574 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI SHEN, LI · 2016 to 2019
$1.9MBioinformatics Strategies for Multidimensional Brain Imaging GeneticsR01LM011360 · NLM · INDIANA UNIVERSITY INDIANAPOLIS · PI MOORE, JASON H., SAYKIN, ANDREW J · 2012 to 2015
$1.4MCIHRNCATS NIH HHS UL1 TR001108NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG019771NIA NIH HHS RC2 AG036535NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG061359NIA NIH HHS U19 AG024904NIBIB NIH HHS R01 EB022574NLM NIH HHS R01 LM011360
Abstract
The pathogenic relevance in Alzheimer's disease (AD) presents a decrease of cerebrospinal fluid amyloid-ß
Indexed as
Genome-Wide Association StudyAgedAged, 80 and overAlzheimer DiseaseAmyloid beta-PeptidesApolipoprotein C-IApolipoproteins ECohort StudiesFemaleHumansMaleMembrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsPeptide FragmentsPolymorphism, Single Nucleotidetau ProteinsAmyloid beta-Peptidesamyloid beta-protein (1-42)APOC1 protein, humanApolipoprotein C-IApolipoproteins EMembrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsPeptide Fragmentstau ProteinsTOMM40 protein, humanADNIAmyloid-ß(42) (Aß(42))Cerebrospinal fluid (CSF)GWISTotal tau (T-tau)T-tau/Aß(42) ratio
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.