Evidence map›Paper›PMID 28640778›Full record

ArticleThe journal of trauma and acute care surgery2018

A cohort study of blunt cerebrovascular injury screening in children: Are they just little adults?

Mackenzie R Cook, Cordelie E Witt, Robert H Bonow, Eileen M Bulger, Ken F Linnau, Saman Arbabi, Bryce R H Robinson, Joseph Cuschieri

Abstract read
In one paragraph

Article in The journal of trauma and acute care surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mackenzie R CookFrom the Division of Trauma, Burn and Critical Care Surgery (M.R.C., C.E.W., E.M.B., S.A., B.R.H.R., J.C.), Harborview Medical Center, Seattle, Washington; Harborview Injury Prevention Research Center (C.E.W., R.H.B., E.M.B., S.A.), Seattle, Washington; Department of Neurological Surgery (R.H.B.), University of Washington, Seattle, Washington; and Department of Radiology (K.F.L.), Harborview Medical Center, Seattle, Washington.
Cordelie E Witt
Robert H Bonow
Eileen M Bulger
Ken F Linnau
Saman Arbabi
Bryce R H Robinson
Joseph Cuschieri
Harborview Medical Center · US

Funding

Pediatric Injury Research Training ProgramT32HD057822 · NICHD · UNIVERSITY OF WASHINGTON · PI CAROLYN A MC CARTY, Ali Rowhani-Rahbar · 2010 to 2026
$4.0M
NICHD NIH HHS T32 HD057822
6 · The paper itself

Abstract

backgroundBlunt cerebrovascular injuries (BCVIs) are rare with nonspecific predictors, making optimal screening critical. Radiation concerns magnify these issues in children. The Eastern Association for the Surgery of Trauma (EAST) criteria, the Utah score (US), and the Denver criteria (DC) have been advocated for pediatric BCVI screening, although direct comparison is lacking. We hypothesized that current screening guidelines inaccurately identify pediatric BCVI.

methodsThis was a retrospective cohort study of pediatric trauma patients treated from 2005 to 2015 with radiographically confirmed BCVI. Our primary outcome was a false-negative screen, defined as a patient with a BCVI who would not have triggered screening.

resultsWe identified 7,440 pediatric trauma admissions, and 96 patients (1.3%) had 128 BCVIs. Median age was 16 years (13, 17 years). A cervical-spine fracture was present in 41%. There were 83 internal carotid injuries, of which 73% were Grade I or II, as well as 45 vertebral injuries, of which 76% were Grade I or II, p = 0.8. More than one vessel was injured in 28% of patients. A cerebrovascular accident (CVA) occurred in 17 patients (18%); eight patients were identified on admission, and nine patients were identified thereafter. The CVA incidence was similar in those with and without aspirin use. The EAST screening missed injuries in 17% of patients, US missed 36%, and DC missed 2%. Significantly fewer injuries would be missed using DC than either EAST or US, p < 0.01.

conclusionsBlunt cerebrovascular injury does occur in pediatric patients, and a significant proportion of patients develop a CVA. The DC appear to have the lowest false-negative rate, supporting liberal screening of children for BCVI. Optimal pharmacotherapy for pediatric BCVI remains unclear despite a relative high incidence of CVA. LEVEL OF EVIDENCE: Diagnostic study, level III.

Indexed as

AdolescentAge FactorsCerebrovascular TraumaChildChild, PreschoolFalse Negative ReactionsHumansMagnetic Resonance ImagingReproducibility of ResultsRetrospective StudiesTomography, X-Ray ComputedWounds, Nonpenetrating

Identifiers

PMID28640778
PMCPMC6469697
OpenAlexW2688084246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.