Evidence map›Paper›PMID 28640446›Full record

ReviewComprehensive Physiology2017

C1q/TNF-Related Protein 3 (CTRP3) Function and Regulation.

Ying Li, Gary L Wright, Jonathan M Peterson

Open access · greenAbstract readReview
In one paragraph

Review in Comprehensive Physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
  2. Article
  3. Putative muscle stem cells promoteProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Unveiling the roles of CTRP family in cardiac remodeling.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Decreased circulating CTRP3 levels in acute and chronic cardiovascular patients.Journal of molecular medicine (Berlin, Germany) · 2024
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ying LiQuillen College of Medicine, Department of Biomedical Sciences, East Tennessee State University, Johnson City, Tennessee, USA.
Gary L WrightQuillen College of Medicine, Department of Biomedical Sciences, East Tennessee State University, Johnson City, Tennessee, USA.
Jonathan M PetersonQuillen College of Medicine, Department of Biomedical Sciences, East Tennessee State University, Johnson City, Tennessee, USA.
East Tennessee State University · US

Funding

The novel adipokine, CTRP3, as an inhibitor of Alcoholic Fatty Liver DiseaseR03AA023612 · NIAAA · EAST TENNESSEE STATE UNIVERSITY · PI PETERSON, JONATHAN M · 2015 to 2016
$146k
NIAAA NIH HHS R03 AA023612
6 · The paper itself

Abstract

As the largest endocrine organ, adipose tissue secretes many bioactive molecules that circulate in blood, collectively termed adipokines. Efforts to identify such metabolic regulators have led to the discovery of a family of secreted proteins, designated as C1q tumor necrosis factor (TNF)-related proteins (CTRPs). The CTRP proteins, adiponectin, TNF-alpha, as well as other proteins with the distinct C1q domain are collectively grouped together as the C1q/TNF superfamily. Reflecting profound biological potency, the initial characterization of these adipose tissue-derived CTRP factors finds wide-ranging effects upon metabolism, inflammation, and survival-signaling in multiple tissue types. CTRP3 (also known as CORS26, cartducin, or cartonectin) is a unique member of this adipokine family. In this review we provide a comprehensive overview of the research concerning the expression, regulation, and physiological function of CTRP3. © 2017 American Physiological Society. Compr Physiol 7:863-878, 2017.

Indexed as

Lipid MetabolismAnimalsCardiovascular DiseasesFatty LiverHumansMetabolic SyndromeTumor Necrosis FactorsC1QTNF3 protein, humanTumor Necrosis Factors

Identifiers

PMID28640446
PMCPMC5756469
OpenAlexW2782232423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.