ArticleeLife2017
Pilot study of large-scale production of mutant pigs by ENU mutagenesis.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Genetically modified pigs: Emerging animal models for hereditary hearing loss.Zoological research · 2024Review
- Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing.Stem cell reports · 2023Article
- Homer 1 genotype AA variant relates to congenital splay leg syndrome in piglets by repressing Pax7 in myogenic progenitors.Frontiers in veterinary science · 2023Article
- SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Recent advances in the regulation mechanism ofJournal of otology · 2022Review
- Genetic insights, disease mechanisms, and biological therapeutics for Waardenburg syndrome.Gene therapy · 2022Review
- Sox10 Gene Is Required for the Survival of Saccular and Utricular Hair Cells in a Porcine Model.Molecular neurobiology · 2022Article
- AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.Nucleic acids research · 2022Article
- Advances in pig models of human diseases.Animal models and experimental medicine · 2022Review
- De novo screening of disease-resistant genes from the chromosome-level genome of rare minnow using CRISPR-cas9 random mutation.GigaScience · 2021Article
- CRISPR/Cas9-mediated correction ofMolecular therapy. Nucleic acids · 2021Article
- Experimental Models for the Study of Hereditary Cornification Defects.Biomedicines · 2021Review
- Congenital Splay Leg Syndrome in Piglets-Current Knowledge and a New Approach to Etiology.Frontiers in veterinary science · 2021Review
- Viewing the current situation of pig model application in China's medical field from the application and funding of NSFC.Journal of otology · 2021Review
- Recent development of AAV-based gene therapies for inner ear disorders.Gene therapy · 2020Review
- A harlequin ichthyosis pig model with a novel ABCA12 mutation can be rescued by acitretin treatment.Journal of molecular cell biology · 2019Article
- A novel pig model capturing clinical symptoms of harlequin ichthyosis.Journal of molecular cell biology · 2019Article
- An exonic splicing enhancer mutation inDisease models & mechanisms · 2019Article
- A novel porcine model reproduces human oculocutaneous albinism type II.Cell discovery · 2019Article
- Rescuing ocular development in an anophthalmic pig by blastocyst complementation.EMBO molecular medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
59 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
N-ethyl-N-nitrosourea (ENU) mutagenesis is a powerful tool to generate mutants on a large scale efficiently, and to discover genes with novel functions at the whole-genome level in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.