SynthesisChinese medical journal2017
Characteristics of Good's Syndrome in China: A Systematic Review.
Synthesis in Chinese medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- When the Good Syndrome Goes Bad: A Systematic Literature Review.Frontiers in immunology · 2021Pooled it
- Good's syndrome and infections in a large retrospective cohort of thymoma.Frontiers in immunology · 2026Article
- Significant decreased CXCR3Frontiers in immunology · 2026Article
- Good's syndrome combined with CMV gastroenteritis: A case report and literature review.Clinical case reports · 2024Article
- Insights from a Case of Good's Syndrome (Immunodeficiency with Thymoma).Biomedicines · 2023Article
- Good's syndrome presenting with CMV pneumonitis and oesophageal candidiasis: A case report.Respirology case reports · 2022Article
- Good's syndrome with diffuse panbronchiolitis as the prominent manifestation: A case and literature review.Respirology case reports · 2021Article
- Granulomatous-lymphocytic Interstitial Lung Disease Associated with Good's Syndrome That Responded to Immunoglobulin Therapy.Internal medicine (Tokyo, Japan) · 2021Article
- Thymoma-Related Paraneoplastic Syndrome Mimicking Reactive Arthritis.Medicina (Kaunas, Lithuania) · 2021Article
- Article
- Good's syndrome with a relapsed bloodstream infection induced byExperimental and therapeutic medicine · 2021Article
- GoodZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021Review
- Recurrent neutropenia and chronic diarrhea following thymectomy: the good, the bad, and the ugly.Journal of community hospital internal medicine perspectives · 2021Article
- Clinicopathologic features of Good's syndrome: Two cases and literature review.Open medicine (Warsaw, Poland) · 2021Article
- Atypical presentation of Good syndrome: acute hepatitis from hepatitis B virus reactivation.Asia Pacific allergy · 2020Article
- Disseminated Mycobacterium abscessus subsp. massiliense infection in a Good's syndrome patient negative for human immunodeficiency virus and anti-interferon-γ autoantibody: a case report.BMC infectious diseases · 2020Article
- Clinical features related to hospital expenses for non-cystic fibrosis bronchiectasis in China.The Journal of international medical research · 2020Article
- Improvement of Good's syndrome by fecal microbiota transplantation: the first case report.The Journal of international medical research · 2019Article
- Good's syndrome, a rare form of acquired immunodeficiency associated with thymomas.Clinics and practice · 2019Article
- A Rare Complication of Thymoma: Pure White Cell Aplasia in Good's Syndrome.Case reports in hematology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGood's syndrome (GS) is a rare disease characterized by thymoma, hypogammaglobulinemia, low or absent B-cells, decreased T-cells, an inverted CD4+/CD8+ T-cell ratio and reduced T-cell mitogen proliferative responses. GS is difficult to diagnose preoperatively due to its rarity and lack of typical symptoms, the characteristics of Chinese GS patients are still lacking. This study aimed to systematically review all the clinical, laboratory, and immunologic findings of reported cases of Chinese patients with GS.
methodsWe searched for case reports and articles up to January 2017 using PubMed, China National Knowledge Infrastructure, Wangfang database and China Science and Technology Journal Database with the following words in combinations as key words: "thymoma," "hypogammaglobulinemia," and "Good's syndrome." The text words and MeSH terms were entered depending on the databases characteristics. The reference lists from retrieved articles were also screened for additional applicable studies. The authors were restricted to Chinese. There was no language restriction.
resultsForty-seven patients were reported in 27 studies. We found that GS has a nationwide distribution and that most cases (83%) have been described on the mainland of China. The initial clinical presentation is varied, ranging from symptoms related to the thymoma to infections resulting from immunodeficiency. Type AB (50%) is the most common histologic type of thymomas in Chinese GS patients according to the World Health Organization classification of thymomas. With respect to infection, sinopulmonary infection (74%) is the most common type, followed by skin infection (10%) and intestinal tract infection (10%). Diarrhea was presented in 36% of patients, and autoimmune manifestations were presented in 36% of patients.
conclusionsGS is a rare association of thymoma and immunodeficiency with a poor prognosis. Astute clinical acumen and increased awareness of the clinical and immunological profile of GS are needed to increase early diagnosis, that would benefit improved therapeutic effects.
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