ArticleAutism research : official journal of the International Society for Autism Research2017
The influence of parental concern on the utility of autism diagnostic instruments.
Article in Autism research : official journal of the International Society for Autism Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
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- Assessing the psychometric properties of the Autism Diagnostic Observation Schedule - Generic (ADOS-G) in a clinical setting in the Chinese mainland.Molecular autism · 2026Article
- Considering context of use in the development, application, and interpretation of autism symptom measures.Developmental medicine and child neurology · 2025Article
- Revolutionizing pediatric neurology care: telemedicine advancements and regulatory impact in the Northeast of Brazil.Arquivos de neuro-psiquiatria · 2025Article
- Measuring autism-associated traits in the general population: Factor structure and measurement invariance across sex and diagnosis status of the Social Communication Questionnaire.Autism : the international journal of research and practice · 2024Article
- Mid-childhood autism sibling recurrence in infants with a family history of autism.Autism research : official journal of the International Society for Autism Research · 2024Article
- Rates of family history of autism and ADHD varies with recruitment approach and socio-economic status.The British journal of developmental psychology · 2024Article
- Bias in assessment of co-occurring mental disorder in individuals with intellectual disabilities: Theoretical perspectives and implications for clinical practice.Journal of intellectual disabilities : JOID · 2024Article
- Autism spectrum disorder in ICD-11-a critical reflection of its possible impact on clinical practice and research.Molecular psychiatry · 2024Review
- Autism Spectrum Disorder and Anxiety Among Transgender Youth: Use of the Social Communication Questionnaire (SCQ).Journal of autism and developmental disorders · 2024Article
- Why are only some children with autism spectrum disorder misclassified by the social communication questionnaire? An empirical investigation of individual differences in sensitivity and specificity in a clinic-referred sample.Journal of neurodevelopmental disorders · 2023Article
- Autism severity and its relationship to disability.Autism research : official journal of the International Society for Autism Research · 2023Article
- Does the severity of autism symptoms change over time? A review of the evidence, impacts, and gaps in current knowledge.Clinical psychology review · 2023Review
- The utility of parent-report screening tools in differentiating autism versus attention-deficit/hyperactivity disorder in school-age children.Autism : the international journal of research and practice · 2022Article
- Autism screening at 18 months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners.Molecular autism · 2022Article
- The Diagnosis of Autism: From Kanner to DSM-III to DSM-5 and Beyond.Journal of autism and developmental disorders · 2021Review
- Identification of the most indicative and discriminative features from diagnostic instruments for children with autism.JCPP advances · 2021Article
- Is the Combination of ADOS and ADI-R Necessary to Classify ASD? Rethinking the "Gold Standard" in Diagnosing ASD.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 3 countries.
Funding
Abstract
The parental report-based Autism Diagnostic Interview-Revised (ADI-R) and the clinician observation-based Autism Diagnostic Observation Schedule (ADOS) have been validated primarily in U.S. clinics specialized in autism spectrum disorder (ASD), in which most children are referred by their parents because of ASD concern. This study assessed diagnostic agreement of the ADOS-2 and ADI-R toddler algorithms in a more broadly based sample of 679 toddlers (age 35-47 months) from the Norwegian Mother and Child Cohort. We also examined whether parental concern about ASD influenced instrument performance, comparing toddlers identified based on parental ASD concern (n = 48) and parent-reported signs of developmental problems (screening) without a specific concern about ASD (n = 400). The ADOS cutoffs showed consistently well-balanced sensitivity and specificity. The ADI-R cutoffs demonstrated good specificity, but reduced sensitivity, missing 43% of toddlers whose parents were not specifically concerned about ASD. The ADI-R and ADOS dimensional scores agreed well with clinical diagnoses (area under the curve ≥ 0.85), contributing additively to their prediction. On the ADI-R, different cutoffs were needed according to presence or absence of parental ASD concern, in order to achieve comparable balance of sensitivity and specificity. These results highlight the importance of taking parental concern about ASD into account when interpreting scores from parental report-based instruments such as the ADI-R. While the ADOS cutoffs performed consistently well, the additive contributions of ADI-R and ADOS scores to the prediction of ASD diagnosis underscore the value of combining instruments based on parent accounts and clinician observation in evaluation of ASD. Autism Res 2017, 10: 1672-1686. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.