Evidence map›Paper›PMID 28639294›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2017

β-Hydroxy-tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE-412.

Ahmad S Altiti, Kai Fan Cheng, Mingzhu He, Yousef Al-Abed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Peptide-based immunotherapy in lupus: Where are we now?Rheumatology and immunology research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ahmad S AltitiCenter for Molecular Innovation, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, 11030, USA.ORCID http://orcid.org/0000-0003-2946-4477
Kai Fan ChengCenter for Molecular Innovation, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, 11030, USA.
Mingzhu HeCenter for Molecular Innovation, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, 11030, USA.
Yousef Al-AbedCenter for Molecular Innovation, The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, New York, 11030, USA.

Funding

Toward a new approach to SLE therapyR01AR057084 · NIAMS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI DIAMOND, BETTY · 2010 to 2014
$1.8M
Developing small molecule therapeutics for lupusR41AR060620 · NIAMS · BIOMEDICAL RESEARCH MODELS, INC. · PI COLEMAN, THOMAS R. · 2011 to 2012
$583k
NIAMS NIH HHS R01 AR057084NIAMS NIH HHS R41 AR060620
6 · The paper itself

Abstract

A new synthetic protocol provides a simple and direct method to generate functionalized β-hydroxy-tetrahydroquinolines (THQs). Hydroboration of quinolines using chloroboranes followed by oxidation with NaBO

Indexed as

BoranesOxidation-ReductionPeptidomimeticsQuinolinesStereoisomerism1,2,3,4-tetrahydroquinolineBoranesFISLE-412PeptidomimeticsQuinolinesbeta-hydroxy-tetrahydroquinolinehydroborationmonochloroboranepeptidomimeticsquinoline

Identifiers

PMID28639294
PMCPMC6003427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.