ArticleEJNMMI research2017
Use of a digital phantom developed by QIBA for harmonizing SUVs obtained from the state-of-the-art SPECT/CT systems: a multicenter study.
Article in EJNMMI research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic value of left ventricular mechanical dyssynchrony indices derived from gated myocardial perfusion SPECT in coronary artery disease: a systematic review and meta-analysis.Annals of nuclear medicine · 2024Pooled it
- EANM practice guideline for quantitative SPECT-CT.European journal of nuclear medicine and molecular imaging · 2023Guideline
- Harmonized quantitative bone SPECT/CT parameters for risk assessment of medication-related osteonecrosis of the jaw: multicenter study.EJNMMI research · 2026Article
- The SwiftScan step-and-shoot continuous mode improves SPECT scanning efficiency: a preliminary phantom and clinical test.EJNMMI physics · 2025Review
- In silico simulation of hepatic arteries: An open-source algorithm for efficient synthetic data generation.Medical physics · 2023Article
- Comparison of the detectability of hot lesions on bone SPECT using six state-of-the-art SPECT/CT systems: a multicenter phantom study to optimize reconstruction parameters.Physical and engineering sciences in medicine · 2023Article
- Impact of bone-equivalent solution density in a thoracic spine phantom on bone single-photon emission computed tomography image quality and quantification.Radiological physics and technology · 2023Article
- Hybrid imaging of neuroendocrine tumors in the heart: Union is strength.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Investigation and optimization of PET-guided SPECT reconstructions for improved radionuclide therapy dosimetry estimates.Frontiers in nuclear medicine · 2023Article
- Optimization ofJournal of applied clinical medical physics · 2022Article
- Development of a new quantification method using partial volume effect correction for individual energy peaks inAsia Oceania journal of nuclear medicine & biology · 2022Article
- Analysis of medication-related osteonecrosis of the jaw with bone SPECT/CT: relationship between patient characteristics and maximum standardized uptake value.Dento maxillo facial radiology · 2021Article
- Impacts of acquisition and reconstruction parameters on the absolute technetium quantification of the cadmium-zinc-telluride-based SPECT/CT system: a phantom study.EJNMMI physics · 2021Article
- Quantitative bone single-photon emission computed tomography imaging for uninfected nonunion: comparison of hypertrophic nonunion and non-hypertrophic nonunion.Journal of orthopaedic surgery and research · 2021Article
- Validation of the influence of CT slice thickness on the quantitative accuracy and image quality of single photon emission computed tomography.Asia Oceania journal of nuclear medicine & biology · 2021Article
- Assessment of inflammatory jaw pathologies using bone SPECT/CT maximum standardized uptake value.Dento maxillo facial radiology · 2020Article
- Phantom and clinical evaluation of bone SPECT/CT image reconstruction with xSPECT algorithm.EJNMMI research · 2020Article
- Towards standardization of absolute SPECT/CT quantification: a multi-center and multi-vendor phantom study.EJNMMI physics · 2019Article
- Does quantification have a role to play in the future of bone SPECT?European journal of hybrid imaging · 2019Review
- Bone SPECT-based segmented attenuation correction for quantitative analysis of bone metastasis (B-SAC): comparison with CT-based attenuation correction.EJNMMI research · 2019Article
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11 authors.
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Abstract
backgroundAlthough quantitative analysis using standardized uptake value (SUV) becomes realistic in clinical single-photon emission computed tomography/computed tomography (SPECT/CT) imaging, reconstruction parameter settings can deliver different quantitative results among different SPECT/CT systems. This study aims to propose a use of the digital reference object (DRO), which is a National Electrical Manufacturers Association (NEMA) phantom-like object developed by the Quantitative Imaging Biomarker Alliance (QIBA) fluorodeoxyglucose-positron emission tomography technical committee, for the purpose of harmonizing SUVs in Tc-99m SPECT/CT imaging.
methodsThe NEMA body phantom with determined Tc-99m concentration was scanned with the four state-of-the-art SPECT/CT systems. SPECT data were reconstructed using different numbers of the product of subset and iteration numbers (SI) and the width of 3D Gaussian filter (3DGF). The mean (SUV
resultsRMSE was lowest in the following reconstruction conditions: SI of 100 and 3DGF of 13 mm for Brightview XCT, SI of 160 and 3DGF of 3 pixels for Discovery NM/CT, SI of 60 and 3DGF of 2 pixels for Infinia, and SI of 140 and 3DGF of 15 mm for Symbia. In pre-harmonized conditions, coefficient of variations (COVs) among the SPECT/CT systems were greater than 10% for all quantitative metrics in three of the spheres, SUV
conclusionsOur proposed method clearly reduced inter-scanner variability in SUVs. A digital phantom developed by QIBA would be useful for harmonizing SUVs in multicenter trials using SPECT/CT.
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