ArticlePlant molecular biology2017
Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.).
Article in Plant molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Abiotic Stress in Crop Production.International journal of molecular sciences · 2023Pooled it
- Molecular and physiological characterization of two sunflower near-isogenic lines with contrasting haplotypes for leaf senescence.BMC plant biology · 2026Article
- Genome-wide bioinformatics analysis of the MATE gene family for abiotic stress tolerance in sunflower (Helianthus annuus L.).PloS one · 2026Article
- The transcriptome-identified gene HaSAPK3.8 of sunflower (Helianthus annuus L.) confers drought resistance in tobacco.BMC plant biology · 2025Article
- Comparative transcriptome and metabolome analyses reveal the mechanism of silicon to improve stem rust resistance in oat (Avena sativa L.).Scientific reports · 2025Article
- Multiomic analysis of the synthetic pathways of secondary metabolites in tobacco leaves at different developmental stages.Frontiers in plant science · 2025Article
- Toward efficient screening systems for sunflower drought tolerance: a comparative and molecular perspective.Frontiers in bioengineering and biotechnology · 2025Article
- Ecophysiological and Molecular Analysis of Contrasting Genotypes for Leaf Senescence in Sunflower (Plants (Basel, Switzerland) · 2024Article
- Multi-Omics Analysis Provides Insights into Green Soybean in Response to Cold Stress.Metabolites · 2024Article
- Drought Tolerance in Plants: Physiological and Molecular Responses.Plants (Basel, Switzerland) · 2024Review
- Growth Properties and Metabolomic Analysis Provide Insight into Drought Tolerance in Barley (International journal of molecular sciences · 2024Article
- Differentially Expressed Genes Identification of Kohlrabi Seedlings (Plants (Basel, Switzerland) · 2024Article
- Comparative transcriptome and coexpression network analysis reveals key pathways and hub candidate genes associated with sunflower (Helianthus annuus L.) drought tolerance.BMC plant biology · 2024Article
- Article
- Abiotic Stress-Induced Leaf Senescence: Regulatory Mechanisms and Application.International journal of molecular sciences · 2023Review
- Review
- Sunflower Hybrids and Inbred Lines Adopt Different Physiological Strategies and Proteome Responses to Cope with Water Deficit.Biomolecules · 2023Article
- Molecular Defensive Mechanism ofInternational journal of molecular sciences · 2023Article
- Similar Transcriptomic Responses to Early and Late Drought Stresses Produce Divergent Phenotypes in Sunflower (International journal of molecular sciences · 2023Article
- Time-course transcriptome and WGCNA analysis revealed the drought response mechanism of two sunflower inbred lines.PloS one · 2022Article
Corrections and comments
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Authors and funding
15 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageBy integration of transcriptional and metabolic profiles we identified pathways and hubs transcription factors regulated during drought conditions in sunflower, useful for applications in molecular and/or biotechnological breeding. Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the mechanisms involved in this tolerance remain unclear at the molecular level. The aim of this study was to characterize and integrate transcriptional and metabolic pathways related to drought stress in sunflower plants, by using a system biology approach. Our results showed a delay in plant senescence with an increase in the expression level of photosynthesis related genes as well as higher levels of sugars, osmoprotectant amino acids and ionic nutrients under drought conditions. In addition, we identified transcription factors that were upregulated during drought conditions and that may act as hubs in the transcriptional network. Many of these transcription factors belong to families implicated in the drought response in model species. The integration of transcriptomic and metabolomic data in this study, together with physiological measurements, has improved our understanding of the biological responses during droughts and contributes to elucidate the molecular mechanisms involved under this environmental condition. These findings will provide useful biotechnological tools to improve stress tolerance while maintaining crop yield under restricted water availability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.