ArticleMolecular diversity2017
Synthesis of substituted 2H-chromenes by a three-component reaction as potential antioxidants.
Article in Molecular diversity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The Chromenopyridine Scaffold: A Privileged Platform in Drug Design.Molecules (Basel, Switzerland) · 2024Review
- Multicomponent synthesis of pyrido[2,3-RSC advances · 2023Article
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Authors and funding
3 authors.
Funding
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Abstract
A series of alkoxy-substituted 2H-chromenes were synthesized by a one-pot three-component reaction using salicylaldehydes, acetyl acetone and alcohol as reactant and medium with tetra-n-butylammonium fluoride (TBAF) as catalyst. Simple reaction conditions, short reaction time and overall good yield of products make this synthetic strategy an efficient one to synthesize 2H-chromene molecules. All the synthesized compounds were evaluated for antioxidant activities. Among all the new compounds, 5j and 5k showed good inhibition [Formula: see text] and [Formula: see text]) at 100 [Formula: see text] concentrations.
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