Evidence map›Paper›PMID 28639042›Full record

ArticleSurgical endoscopy2018

Comparative study between endoscopic submucosal dissection and surgery in patients with early gastric cancer.

Kyu Yeon Hahn, Chan Hyuk Park, Yong Kang Lee, Hyunsoo Chung, Jun Chul Park, Sung Kwan Shin, Yong Chan Lee, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung and 2 more

Open access · greenAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 7 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 7 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. [Clinical Practice Guideline for Endoscopic Resection of Early Gastrointestinal Cancer].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020
    Guideline
  7. Comparison of Long-Term Outcomes of Endoscopic Submucosal Dissection and Surgery for Early Gastric Cancer: a Systematic Review and Meta-analysis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Pooled it
  8. Trial
  9. A preoperative risk-scoring model for predicting intraoperative hemorrhage during endoscopic submucosal dissection for gastric neoplasms.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. The index endoscopic characteristics associated with gastric neoplasms in serial screening of upper gastrointestinal endoscopy.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. PANoptosis subtypes predict prognosis and immune efficacy in gastric cancer.Apoptosis : an international journal on programmed cell death · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Kyu Yeon HahnDepartment of Internal Medicine, Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Chan Hyuk ParkDepartment of Internal Medicine, Guri Hospital, Hanyang University College of Medicine, Seoul, Korea.
Yong Kang LeeDepartment of Internal Medicine, Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Hyunsoo ChungDepartment of Internal Medicine and Liver Research Institute, Seoul National University of Medicine, Seoul, Korea.
Jun Chul ParkDepartment of Internal Medicine, Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Sung Kwan ShinDepartment of Internal Medicine, Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Yong Chan LeeDepartment of Internal Medicine, Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Hyoung-Il KimDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Jae-Ho CheongDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Woo Jin HyungDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Sung Hoon NohDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Sang Kil LeeDepartment of Internal Medicine, Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. sklee@yuhs.ac.
Severance Hospital · KRYonsei University · KRHanyang University Guri Hospital · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic submucosal dissection (ESD) is accepted as a standard treatment in patients with early gastric cancer (EGC) who have a negligible risk of lymph node metastasis. The aim of this study was to compare the short-term and long-term outcomes between ESD and surgery in patients with EGC that fulfilled the expanded indication of ESD on their final pathologic report.

methodsWe reviewed the clinical data of patients who underwent gastric ESD and surgery between January 2007 and December 2012. Patients with pathologically confirmed EGC that fulfilled the expanded indication of ESD on their final pathologic report were analyzed.

resultsAmong 2023 patients, 817 (40.4%) underwent ESD and 1206 (59.6%) underwent surgery. The proportion of cases meeting the absolute indication was significantly higher in the ESD group than in the surgery group (66.0 vs. 26.2%). Lesions on the middle third, >3 cm in size, flat or depressed, and of undifferentiated histology were significantly more common in the surgery group than in the ESD group. The ESD group showed lower acute complication rates [8.1% (66 of 817) vs. 18.1% (218 of 1206), P ≤ 0.001] and procedure-related mortality [0 vs. 0.3% (4 of 1206), P = 0.153] than the surgical group. The annual incidence of recurrent gastric cancer was 2.18% in the ESD group and 0.19% in the surgery group. The 5-year overall and disease-specific survival rates were not significantly different between the ESD group and the surgery group (overall survival: 96.4 vs. 97.2%, P = 0.423; disease-specific survival: 99.6 vs. 99.2%, P = 0.203).

conclusionsAlthough EGC lesions had poorer features in the surgery group than in the ESD group, ESD was comparable to surgery for EGCs that fulfilled the expanded indication of ESD, with lower rates of acute complication and comparable overall survival.

Indexed as

AgedEndoscopic Mucosal ResectionFemaleFollow-Up StudiesGastrectomyHumansMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesStomachStomach NeoplasmsSurvival RateTreatment OutcomeAbsolute indicationEndoscopic submucosal dissectionExpanded indicationOutcomesUndifferentiated histology

Identifiers

PMID28639042
OpenAlexW2639102888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.