SynthesisEuropean archives of psychiatry and clinical neuroscience2018
Is electroconvulsive therapy an evidence-based treatment for catatonia? A systematic review and meta-analysis.
Synthesis in European archives of psychiatry and clinical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology.Journal of psychopharmacology (Oxford, England) · 2023Guideline
- Non-invasive brain stimulation for treating catatonia: a systematic review.Frontiers in psychiatry · 2023Pooled it
- Therapeutic intensification in post-traumatic stress disorder worldwide: where do we stand?European journal of psychotraumatology · 2026Review
- Electroconvulsive Therapy for Catatonia in Autistic and Non-Autistic Patients: An Observational Study on Course, Efficacy, Aggression, and Self-Injury Outcomes.Autism research : official journal of the International Society for Autism Research · 2026Article
- ECT and Delirium: Literature Review and a Pediatric Case Report.Current psychiatry reports · 2025Review
- Guideline for pharmacological treatment of schizophrenia 2022.Neuropsychopharmacology reports · 2025Article
- Clinical predictors of short-term treatment response in stupor: a retrospective study.Frontiers in psychiatry · 2025Article
- Catatonia and epilepsy: An underappreciated relationship.Epilepsy & behavior : E&B · 2024Review
- Case report: Down syndrome regression disorder, catatonia, and psychiatric and immunomodulatory interventions.Frontiers in psychiatry · 2024Article
- Clinical Practice Guidelines for the Use of Electroconvulsive Therapy.Indian journal of psychiatry · 2023Article
- Moving to accelerated protocols of tDCS in catatonia: a case report.Frontiers in psychiatry · 2023Article
- Plasmapheresis for a Patient with Catatonia and Systemic Lupus Erythematosus: A Case Report and Literature Review.Journal of clinical medicine · 2022Article
- Symptomatic Profile of Cariprazine in the Context of ICD-11 Domains for Schizophrenia: Review of Clinically Oriented Studies: Симптоматический профиль карипразина в контексте доменов шизофрении в МКБ -11: обзор клинически ориентированных исследований.Consortium psychiatricum · 2022Review
- Recurrent Catatonia due to Episodic Obsessive-Compulsive Disorder.Case reports in psychiatry · 2022Article
- History of ECT in Schizophrenia: From Discovery to Current Use.Schizophrenia bulletin open · 2022Article
- Efficacy of Transcranial Direct-Current Stimulation in Catatonia: A Review and Case Series.Frontiers in psychiatry · 2022Article
- Distinct predictors of short- versus long-term depression outcomes following electroconvulsive therapy.Journal of psychiatric research · 2022Article
- [Evolution of electro-convulsive therapy activity in France since the beginning of the COVID-19 pandemic].L'Encephale · 2020Article
- Electroconvulsive Therapy for Patients with Catatonia: Current Perspectives.Neuropsychiatric disease and treatment · 2020Review
- Structure and neural mechanisms of catatonia.The lancet. Psychiatry · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to review and discuss the evidence-based arguments for the efficacy of electroconvulsive therapy (ECT) in the treatment of catatonia. Randomized controlled trials (RCTs) and observational studies focusing on the response to ECT in catatonia were selected in PubMed, the Cochrane Library, Embase, ClinicalTrials.gov and Current Controlled Trials through October 2016 and qualitatively described. Trials assessing pre-post differences using a catatonia or clinical improvement rating scale were pooled together using a random effect model. Secondary outcomes were adverse effects of anesthesia and seizure. 564 patients from 28 studies were included. RCTs were of low quality and were heterogeneous; therefore, it was not possible to combine their efficacy results. An improvement of catatonic symptoms after ECT treatment was evidenced in ten studies (SMD = -3.14, 95% CI [-3.95; -2.34]). The adverse effects that were reported in seven studies included mental confusion, memory loss, headache, or adverse effects associated with anesthesia. ECT protocols were heterogeneous. The literature consistently describes improvement in catatonic symptoms after ECT. However, the published studies fail to demonstrate efficacy and effectiveness. It is now crucial to design and perform a quality RCT to robustly validate the use of ECT in catatonia.Prospero registration information: PROSPERO 2016: CRD42016041660.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.