Evidence map›Paper›PMID 28638850›Full record

ArticleJournal of probiotics & health2017

Probiotic

Brian P Blackwood, Carrie Y Yuan, Douglas R Wood, Joseph D Nicolas, Justyna S Grothaus, Catherine J Hunter

Open access · greenAbstract read
In one paragraph

Article in Journal of probiotics & health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 1 synthesis or guideline pooled it, 171 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Tight junction proteins and intestinal health in preterm infants.Journal of neonatal-perinatal medicine · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Probiotics and the intestinal tight junction barrier function.Frontiers in cell and developmental biology · 2025
    Review
  18. Article
  19. GABA-producingMicrobiome research reports · 2025
    Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Brian P BlackwoodAnn and Robert H. Lurie Children's Hospital of Chicago, Department of Pediatric Surgery, Chicago, Illinois, USA.
Carrie Y YuanNorthwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, Illinois, USA.
Douglas R WoodNorthwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, Illinois, USA.
Joseph D NicolasNorthwestern University Feinberg School of Medicine, Department of Pediatrics, Chicago, Illinois, USA.
Justyna S GrothausAnn and Robert H. Lurie Children's Hospital of Chicago, Department of Pediatric Surgery, Chicago, Illinois, USA.
Catherine J HunterAnn and Robert H. Lurie Children's Hospital of Chicago, Department of Pediatric Surgery, Chicago, Illinois, USA.
Northwestern University · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9M
Defining bacterial virulence, cAMP and PKA in necrotizing enterocolitisK08DK106450 · NIDDK · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HUNTER, CATHERINE JANE · 2015 to 2021
$851k
NCI NIH HHS P30 CA060553NIDDK NIH HHS K08 DK106450
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) is a serious intestinal disease that occurs in newborn infants. It is associated with major morbidity and affects 5% of all infants admitted to neonatal intensive care units. Probiotics have variable efficacy in preventing necrotizing enterocolitis. Tight junctions (TJ) are protein complexes that maintain epithelial barrier integrity. We hypothesized that the probiotics

Indexed as

Barrier functionLactobacillusNecrotizing enterocolitisProbioticTight junctions

Identifiers

PMID28638850
PMCPMC5475283
OpenAlexW2599303917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.