Evidence map›Paper›PMID 28638781›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2017

Bioinspired Mechano-Sensitive Macroporous Ceramic Sponge for Logical Drug and Cell Delivery.

Changlu Xu, Zhihao Wei, Huajian Gao, Yanjie Bai, Huiling Liu, Huilin Yang, Yuekun Lai, Lei Yang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 35 citations in OpenAlex.

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  10. Bioinspired Mechano-Sensitive Macroporous Ceramic Sponge for Logical Drug and Cell Delivery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Changlu XuOrthopaedic Institute Department of Orthopaedics The First Affiliated Hospital Soochow University Suzhou Jiangsu 215006 P. R. China.
Zhihao WeiOrthopaedic Institute Department of Orthopaedics The First Affiliated Hospital Soochow University Suzhou Jiangsu 215006 P. R. China.
Huajian GaoSchool of Engineering Brown University Providence RI 02912 USA.
Yanjie BaiSchool of Public Health Medical College Soochow University Suzhou Jiangsu 215123 P. R. China.
Huiling LiuOrthopaedic Institute Department of Orthopaedics The First Affiliated Hospital Soochow University Suzhou Jiangsu 215006 P. R. China.
Huilin YangOrthopaedic Institute Department of Orthopaedics The First Affiliated Hospital Soochow University Suzhou Jiangsu 215006 P. R. China.
Yuekun LaiNational Engineering Laboratory for Modern Silk College of Textile and Clothing Engineering Soochow University Suzhou Jiangsu 215123 P. R. China.ORCID 0000-0003-4100-510X
Lei YangOrthopaedic Institute Department of Orthopaedics The First Affiliated Hospital Soochow University Suzhou Jiangsu 215006 P. R. China.
Soochow University · CNBrown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

On-demand, ultrahigh precision delivery of molecules and cells assisted by scaffold is a pivotal theme in the field of controlled release, but it remains extremely challenging for ceramic-based macroporous scaffolds that are prevalently used in regenerative medicine. Sea sponges (Phylum Porifera), whose bodies possess hierarchical pores or channels and organic/inorganic composite structures, can delicately control water intake/circulation and therefore achieve high precision mass transportation of food, oxygen, and wastes. Inspired by leuconoid sponge, in this study, the authors design and fabricate a biomimetic macroporous ceramic composite sponge (CCS) for high precision logic delivery of molecules and cells regulated by mechanical stimulus. The CCS reveals unique on-demand AND logic release behaviors in response to dual-gates of moisture and pressure (or strain) and, more importantly, 1 cm

Indexed as

bioinspired materialcell deliverylogic deliverymechanically activeporous ceramic

Identifiers

PMID28638781
PMCPMC5473326
OpenAlexW2609666880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.