Evidence map›Paper›PMID 28638777›Full record

ArticleChemistryOpen2017

Heterobifunctional Dyes: Highly Fluorescent Linkers Based on Cyanine Dyes.

Virginia Wycisk, Katharina Achazi, Ole Hirsch, Christian Kuehne, Jens Dernedde, Rainer Haag, Kai Licha

Abstract read
In one paragraph

Article in ChemistryOpen, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Virginia WyciskInstitute of Chemistry and Biochemistry Freie Universität Berlin Takustr. 3 14195 Berlin Germany.
Katharina AchaziInstitute of Chemistry and Biochemistry Freie Universität Berlin Takustr. 3 14195 Berlin Germany.
Ole HirschPhysikalisch-Technische Bundesanstalt Abbestr. 2-12 10587 Berlin Germany.
Christian KuehneInstitute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry Charité-Universitätsmedizin Berlin Augustenburger Platz 113353 Berlin Germany.
Jens DerneddeInstitute of Laboratory Medicine, Clinical Chemistry and Pathobiochemistry Charité-Universitätsmedizin Berlin Augustenburger Platz 113353 Berlin Germany.
Rainer HaagInstitute of Chemistry and Biochemistry Freie Universität Berlin Takustr. 3 14195 Berlin Germany.
Kai LichaInstitute of Chemistry and Biochemistry Freie Universität Berlin Takustr. 3 14195 Berlin Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we present a new synthetic route to cyanine-based heterobifunctional dyes and their application as fluorescent linkers between polymers and biomolecules. The synthesized compounds, designed in the visible spectral range, are equipped with two different reactive groups for highly selective conjugation under physiological conditions. By applying indolenine precursors with functionalized benzenes, we achieved water-soluble asymmetric cyanine dyes bearing maleimido and

Indexed as

antibodiesconjugationdyes/pigmentsfluorescenceheterobifunctional linkers

Identifiers

PMID28638777
PMCPMC5474662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.