ArticleBrain and behavior2017
Childhood trauma and negative memory bias as shared risk factors for psychopathology and comorbidity in a naturalistic psychiatric patient sample.
Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 61 citations in OpenAlex.
- The effectiveness and neurobiological actions of memory bias modification: a randomized controlled trial.Psychological medicine · 2025Trial
- Randomized Trial on the Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: A Path Analytic and Supervised Machine-Learning Study.International journal of environmental research and public health · 2022Trial
- Associations Between Traumatic Event Exposure and Depressive Symptoms Among Chinese University Freshmen: A Conditional Process Analysis of Interpersonal Difficulties and Only-Child Status.Behavioral sciences (Basel, Switzerland) · 2026Article
- Neural bias to social feedback moderates link between childhood abuse and subsequent harsh parenting.Social cognitive and affective neuroscience · 2026Article
- Impacts of early life adversity on the neurocircuitry of emotional memory in children.Development and psychopathology · 2025Article
- Attachment Insecurity Mediates the Associations Between Childhood Trauma and Duration of Emotions During a Laboratory-Based Sexual Conflict Discussion Among Couples.Archives of sexual behavior · 2025Article
- Early maladaptive schemas from child maltreatment in depression and psychotherapeutic remediation: a predictive coding framework.Frontiers in psychiatry · 2025Review
- Parental Alcohol Intoxication, Adverse Childhood Experiences, and Negative Psychological Reactions to Childhood Adversities: Cross-Sectional and Prospective Data from the Population‑Based HUNT Study.Journal of child & adolescent trauma · 2024Article
- Childhood adversity, stress reactivity, and structural brain measures in stress-related/neurodevelopmental disorders, and their comorbidity: A large transdiagnostic cross-sectional study.Human brain mapping · 2024Article
- Childhood adversity predicts striatal functional connectivity gradient changes after acute stress.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Social feedback biases emerge during recall but not prediction and shift across the development of social anxiety.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Usability of the Experience Sampling Method in Specialized Mental Health Care: Pilot Evaluation Study.JMIR formative research · 2023Article
- Transdiagnostic phenomena of psychopathology in the context of the RDoC: protocol of a multimodal cross-sectional study.BMC psychology · 2023Article
- High levels of childhood trauma associated with changes in hippocampal functional activity and connectivity in young adults during novelty salience.European archives of psychiatry and clinical neuroscience · 2023Article
- Signatures of exposure to childhood trauma in young adults in the structure and neurochemistry of the superior temporal gyrus.Journal of psychopharmacology (Oxford, England) · 2023Article
- Psychosocial Profiles of Patients Admitted to Psychiatric Emergency Services: Results from the Signature Biobank Project.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2022Article
- Article
- The impact of childhood maltreatment on adaptive emotion regulation strategies.Child abuse & neglect · 2022Article
- Challenging the negative learning bias hypothesis of depression: reversal learning in a naturalistic psychiatric sample.Psychological medicine · 2022Article
- Is a Negative Attentional Bias in Individuals with Autism Spectrum Disorder Explained by Comorbid Depression? An Eye-Tracking Study.Journal of autism and developmental disorders · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBoth childhood trauma and negative memory bias are associated with the onset and severity level of several psychiatric disorders, such as depression and anxiety disorders. Studies on these risk factors, however, generally use homogeneous noncomorbid samples. Hence, studies in naturalistic psychiatric samples are lacking. Moreover, we know little about the quantitative relationship between the frequency of traumatic childhood events, strength of memory bias and number of comorbid psychiatric disorders; the latter being an index of severity. The current study examined the association of childhood trauma and negative memory bias with psychopathology in a large naturalistic psychiatric patient sample.
methodsFrequency of traumatic childhood events (emotional neglect, psychological-, physical- and sexual abuse) was assessed using a questionnaire in a sample of 252 adult psychiatric patients with no psychotic or bipolar-I disorder and no cognitive disorder as main diagnosis. Patients were diagnosed for DSM-IV Axis-I and Axis-II disorders using a structured clinical interview. This allowed for the assessment of comorbidity between disorders. Negative memory bias for verbal stimuli was measured using a computer task.
resultsLinear regression models revealed that the frequency of childhood trauma as well as negative memory bias was positively associated with psychiatric comorbidity, separately and above and beyond each other (all
conclusionsThe results indicate that childhood trauma and negative memory bias may be of importance for a broader spectrum of psychiatric diagnoses, besides the frequently studied affective disorders. Importantly, frequently experiencing traumatic events during childhood increases the risk of comorbid psychiatric disorders.
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