ReviewJournal of clinical and experimental dentistry2017
Importance and methodologies of endodontic microleakage studies: A systematic review.
Review in Journal of clinical and experimental dentistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of an Intraorifice Barrier on Endodontically Treated Teeth: A Systematic Review and Meta-Analysis of In Vitro Studies.BioMed research international · 2022Pooled it
- Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial.Clinical oral investigations · 2024Trial
- In vitro evaluation of the sealing ability of combined use of iRoot BP Plus and iRoot SP for root-end filling.Clinical oral investigations · 2023Trial
- Article
- A Novel Laboratorial Approach to Evaluate Bacterial Microleakage of Endodontic Sealers.Current protocols · 2026Article
- Evaluation of various obturation techniques with AH Plus Jet sealer in simulated C-shaped canals.The Saudi dental journal · 2026Article
- A micro-CT-integrated 3D simulation framework reveals fluid transport mechanisms and void dynamics in root canal biomaterials.Scientific reports · 2026Article
- Correlation of dentinal penetration and microleakage of bioceramic with calcium hydroxide and resin based root canal sealers- A CLSM study.Journal of conservative dentistry and endodontics · 2026Article
- Assessment of Sealing Ability and Degradation Resistance of a Hydrogel-Based Root Canal Filling Material Using a Bacterial Leakage Model and SEM Analysis.BioMed research international · 2026Article
- Sealing ability of nano-bioactive glass, Bio-C repair, and EndoSequence Bioceramic-root Repair Material putty as root end restoratives: A confocal laser microscopic study.Journal of conservative dentistry and endodontics · 2026Article
- Critical analysis of the "nanoleakage concept" in endodontics: a narrative review.Frontiers in dental medicine · 2026Review
- Coronal microleakage of two intraorifice bioceramic barriers in single-rooted premolars:Dental research journal · 2026Article
- Evaluation of the apical sealing ability of bioRoot RCS with Various Gutta-percha cones using spectrophotometry and scanning electron microscopy: anFrontiers in dental medicine · 2026Article
- In Vitro Techniques for Microleakage Evaluation of Coronary Restorative Materials: A Scoping and Mapping Review.Journal of functional biomaterials · 2025Review
- Comparative evaluation of microleakage of four restorative materials using confocal laser scanning microscopy: an in vitro study.Irish journal of medical science · 2025Article
- Comparative evaluation of sealing potential of mineral trioxide aggregate, biodentine, and bio-C repair in furcation perforations: A glucose penetration study.Journal of conservative dentistry and endodontics · 2025Article
- Studying the Effect of Four Postspace Preparation Techniques on the Apical Seal Integrity of the Root Canals Obturated With the Resilon/RealSeal System and the Lateral Condensation Technique.International journal of dentistry · 2025Article
- Effects of a Universal Adhesive System and the Snow-Plow Technique on Microleakage of Class II Composite Restorations in Primary Molars.Frontiers in dentistry · 2025Article
- Bacterial Leakage Testing in Dentistry: A Comprehensive Review on Methods, Models, and Clinical Relevance.Scientifica · 2025Review
- Comparative Analysis of Fracture Resistance of Endodontic Sealer Types and Filling Methods.Materials (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIt is very important to obtain a tight seal in obturated root canal, making it necessary to conduct clinical or laboratory studies on the sealability of endodontic materials. Different methodologies have been historically used to assess microleakage of different endodontic materials. The aim of the present study was to comprehensively review different material testing methods used in microleakage studies, their interpretation and importance in endodontic literature. MATERIAL AND
methodsA systematic search was conducted in Medline, Cochrane, and Web of Science databases. In addition, the reference lists of review articles on the topic were searched. No language restriction was applied. Two independent reviewers screened the article.
resultsMicroleakage is considered the single most important risk factor responsible for apical periodontitis. Dye penetration, dye diffusion, bacterial and endototoxin infiltration, fluid filtration, glucose, caffeine and protein infiltration, radioisotope penetration, animal studies, and electrochemical or 3D evaluation are different methodologies used to assess dental leakage. 91 out of 177 articles in the primary search were included in the study. These methods are very divergent in their viewpoints; that is why their results cannot be easily compared. It is necessary to standardize microleakage detection methods in order to more correctly evaluate the phenomena that are found between the root canal wall and the root canal filling materials.
conclusionsAll the methods are useful if studies are performed strictly with large sample sizes and proper control groups and if the technique can be standardized. Furthermore, more evaluations of the reliability of the methods are strongly recommended.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.