Evidence map›Paper›PMID 28638559›Full record

ArticleJournal of clinical and experimental dentistry2017

Comparative Evaluation of Anti Microbial effects of Triple Antibiotic Paste and Amox and its derivatives against

Manjeet Kaur, Shrikant Kendre, Parmod Gupta, Navneet Singh, Harsimran Sethi, Neha Gupta, Rushil Acharya

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Antimicrobial Efficacy of Intracanal Medicaments againstInternational journal of dentistry · 2020
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Manjeet KaurMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Shrikant KendreMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Parmod GuptaMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Navneet SinghMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Harsimran SethiMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Neha GuptaMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Rushil AcharyaMaharaja Ganga Singh Dental College and Research Centre 11LNT Hanumangarh Road, Shri Ganganagar, Rajasthan.
Mahatma Gandhi Dental College & Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimTo observe the potential of combinations [(Amoxicillin+ Metronidazole, Amoxicillin Clavulanic Acid + Metronidazole; Amoxicillin and Cloxacillin + Metronidazole)] over Triple Antibiotic Paste. MATERIAL AND

methodsFifty single rooted teeth free from dental caries were selected for the study. Teeth were cut at equal distance from root apex (13mm from apex) with sterile diamond disk and straight hand piece for standardization of root length. The opening of root canal was enlarged with engine driven pro-taper files. To remove the organic and inorganic debris, canal was cleaned with 17% EDTA followed by 2.5% NaOCl for 5min. Distilled water irrigation was done for 5 min to remove any traces of used chemical and then sterilized in autoclave at 1200c for 15 min. at 15 lbs pressure. Bacteria cultured on blood agar plate and at the same time fresh antibiotic combinations were made and placed in the root canals, then incubated in the incubator, under sterile conditions and observed at 24hrs, 48hr and 72hrs.

resultsThe largest inhibition zones were observed for the Triple Antibiotic Paste, followed by Amoxicillin and Clavulanic acid + Metronidazole group however, the clearest zones were achieved with Amoxicillin and Clavlunic acid + Metronidazole group and the smallest for Amoxicillin and Metronidazole group.

conclusionsThe results suggest that though Triple antibiotic showed the maximum inhibition, Amoxicillin and Clavulanic acid combination along with Metronidazole gave the most reliable results. Further studies using the different combinations and different concentrations along with different methods of increasing the shelf life of such medications can be undertaken.

Identifiers

PMID28638559
PMCPMC5474338
OpenAlexW2620261226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.