ArticleTheranostics2017
Dual-Responsive Molecular Probe for Tumor Targeted Imaging and Photodynamic Therapy.
Article in Theranostics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Photobleaching-mediated charge-convertible cyclodextrin nanoparticles achieve deep tumour penetration for rectal cancer theranostics.Nature nanotechnology · 2024Article
- Small molecules and conjugates as theranostic agents.RSC chemical biology · 2023Review
- A tumor-targetable NIR probe with photoaffinity crosslinking characteristics for enhanced imaging-guided cancer phototherapy.Chemical science · 2023Article
- Emergence of Raman Spectroscopy as a Probing Tool for Theranostics.Nanotheranostics · 2023Review
- Design Principles Governing the Development of Theranostic Anticancer Agents and Their Nanoformulations with Photoacoustic Properties.Pharmaceutics · 2022Review
- Research progress on SLC7A11 in the regulation of cystine/cysteine metabolism in tumors.Oncology letters · 2022Review
- Activatable NIR-II organic fluorescent probes for bioimaging.Theranostics · 2022Review
- Potential of Cyanine Derived Dyes in Photodynamic Therapy.Pharmaceutics · 2021Review
- Recent Advances in Cyanine-Based Phototherapy Agents.Frontiers in chemistry · 2021Review
- Research progress of near-infrared fluorescence probes based on indole heptamethine cyanine dyes in vivo and in vitro.BMC chemistry · 2020Review
- A singlet oxygen self-reporting photosensitizer for cancer phototherapy.Chemical science · 2020Article
- Near-Infrared Fluorescent pH Responsive Probe for Targeted Photodynamic Cancer Therapy.Scientific reports · 2020Article
- pH-responsive perylenediimide nanoparticles for cancer trimodality imaging and photothermal therapy.Theranostics · 2020Article
- Activatable molecular agents for cancer theranostics.Chemical science · 2019Review
- A Turn-On Optoacoustic Probe for Imaging Metformin-Induced Upregulation of Hepatic Hydrogen Sulfide and Subsequent Liver Injury.Theranostics · 2019Article
- An Activatable Near-Infrared Chromophore for Multispectral Optoacoustic Imaging of Tumor Hypoxia and for Tumor Inhibition.Theranostics · 2019Article
- Tumor Size-Dependent Anticancer Efficacy of Chlorin Derivatives for Photodynamic Therapy.International journal of molecular sciences · 2018Article
- Endogenous pH-responsive nanoparticles with programmable size changes for targeted tumor therapy and imaging applications.Theranostics · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The precision oncology significantly relies on the development of multifunctional agents to integrate tumor targeting, imaging and therapeutics. In this study, a first small-molecule theranostic probe, RhoSSCy is constructed by conjugating 5'-carboxyrhodamines (Rho) and heptamethine cyanine IR765 (Cy) using a reducible disulfide linker and pH tunable amino-group to realize thiols/pH dual sensing.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.