Evidence map›Paper›PMID 28638431›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2017

Erzhi Pill® Repairs Experimental Liver Injury via TSC/mTOR Signaling Pathway Inhibiting Excessive Apoptosis.

Bu-Gao Zhou, Hai-Mei Zhao, Xiu-Yun Lu, Xin Wang, Yong Zou, Rong Xu, Hai-Yang Yue, Yi Liu, Zheng-Yun Zuo, Duan-Yong Liu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Erzhi PillFrontiers in pharmacology · 2018
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bu-Gao ZhouScience and Technology College, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Hai-Mei ZhaoSchool of Basic Medical Sciences, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.ORCID 0000-0001-8767-5251
Xiu-Yun LuScience and Technology College, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Xin WangDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Yong ZouDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Rong XuDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Hai-Yang YueDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Yi LiuDepartment of Postgraduate, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.
Zheng-Yun ZuoAffiliated Hospital, Science and Technology College, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330006, China.ORCID 0000-0001-7082-7167
Duan-Yong LiuScience and Technology College, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330004, China.ORCID 0000-0003-2855-2811
Jiangxi University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to investigate the mechanism of hepatoprotective effect of Erzhi Pill (EZP) on the liver injury via observing TSC/mTOR signaling pathway activation. The experimental liver injury was induced by 2-acetylaminofluorene (2-AAF) treatment combined with partial hepatectomy (PH). EZP treated 2-AAF/PH-induced liver injury by the therapeutic and prophylactic administration. After the administration of EZP, the activities of aspartic transaminase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AKP), and gamma-glutamyl transpeptidase (

Identifiers

PMID28638431
PMCPMC5468563
OpenAlexW2619542275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.