Evidence map›Paper›PMID 28638414›Full record

ReviewStem cells international2017

An Examination of the Role of Transcriptional and Posttranscriptional Regulation in Rhabdomyosarcoma.

Alexander J Hron, Atsushi Asakura

Abstract readReview
In one paragraph

Review in Stem cells international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander J HronStem Cell Institute, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0002-4634-9393
Atsushi AsakuraStem Cell Institute, University of Minnesota Medical School, Minneapolis, MN 55455, USA.ORCID 0000-0001-8078-1027

Funding

Genetically Engineered Muscle Stem Cell Transplantation for Muscular Dystrophy...R01AR062142 · NIAMS · UNIVERSITY OF MINNESOTA · PI ASAKURA, ATSUSHI · 2012 to 2016
$1.6M
Engineering iPSC-Derived Skeletal Muscle and Cells for TransplantationR21AR070319 · NIAMS · UNIVERSITY OF MINNESOTA · PI ASAKURA, ATSUSHI · 2016 to 2017
$372k
NIAMS NIH HHS R01 AR062142NIAMS NIH HHS R21 AR070319
6 · The paper itself

Abstract

Rhabdomyosarcoma (RMS) is an aggressive family of soft tissue tumors that most commonly manifests in children. RMS variants express several skeletal muscle markers, suggesting myogenic stem or progenitor cell origin of RMS. In this review, the roles of both recently identified and well-established microRNAs in RMS are discussed and summarized in a succinct, tabulated format. Additionally, the subtypes of RMS are reviewed along with the involvement of basic helix-loop-helix (bHLH) proteins, Pax proteins, and microRNAs in normal and pathologic myogenesis. Finally, the current and potential future treatment options for RMS are outlined.

Identifiers

PMID28638414
PMCPMC5468592

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.