Evidence map›Paper›PMID 28638383›Full record

ArticleFrontiers in immunology2017

Non-canonical Glucocorticoid Receptor Transactivation of

Hang Pong Ng, Scott Jennings, Jack Wang, Patricia E Molina, Steve Nelson, Guoshun Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hang Pong NgAlcohol and Drug Abuse Center, Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Scott JenningsAlcohol and Drug Abuse Center, Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Jack WangAlcohol and Drug Abuse Center, Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Patricia E MolinaDepartment of Physiology, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Steve NelsonDepartment of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Guoshun WangAlcohol and Drug Abuse Center, Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, United States.
Louisiana State University Health Sciences Center New Orleans · US

Funding

Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI DAVID A WELSH · 2004 to 2026
$42.6M
Alcohol, GILZ and LPS SepsisR21AA024549 · NIAAA · LSU HEALTH SCIENCES CENTER · PI WANG, GUOSHUN · 2016 to 2017
$374k
Systematic Responses of GILZ Regulatory Network to AlcoholR21AA021824 · NIAAA · LSU HEALTH SCIENCES CENTER · PI WANG, GUOSHUN · 2013 to 2014
$372k
NIAAA NIH HHS P60 AA009803NIAAA NIH HHS R21 AA021824NIAAA NIH HHS R21 AA024549
6 · The paper itself

Abstract

Acute alcohol exposure suppresses cell inflammatory response. The underlying mechanism has not been fully defined. Here we report that alcohol was able to activate glucocorticoid receptor (GR) signaling in the absence of glucocorticoids (GCs) and upregulated glucocorticoid-induced leucine zipper (

Indexed as

alcoholglucocorticoidglucocorticoid-induced leucine zipperglucocorticoid receptorinflammatory responseLPS

Identifiers

PMID28638383
PMCPMC5461336
OpenAlexW2621767694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.