Evidence map›Paper›PMID 28638371›Full record

ArticleFrontiers in microbiology2017

The Anticancer Peptide TAT-RasGAP

Mathieu Heulot, Nicolas Jacquier, Sébastien Aeby, Didier Le Roy, Thierry Roger, Evgeniya Trofimenko, David Barras, Gilbert Greub, Christian Widmann

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  9. TAT-RasGAPProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mathieu HeulotDepartment of Physiology, University of LausanneLausanne, Switzerland.
Nicolas JacquierDepartment of Laboratories, Institute of Microbiology, Lausanne University Hospital and University of LausanneLausanne, Switzerland.
Sébastien AebyDepartment of Laboratories, Institute of Microbiology, Lausanne University Hospital and University of LausanneLausanne, Switzerland.
Didier Le RoyInfectious Diseases Service, Lausanne University HospitalEpalinges, Switzerland.
Thierry RogerInfectious Diseases Service, Lausanne University HospitalEpalinges, Switzerland.
Evgeniya TrofimenkoDepartment of Physiology, University of LausanneLausanne, Switzerland.
David BarrasBioinformatics Core Facility, Swiss Institute of BioinformaticsLausanne, Switzerland.
Gilbert GreubDepartment of Laboratories, Institute of Microbiology, Lausanne University Hospital and University of LausanneLausanne, Switzerland.
Christian WidmannDepartment of Physiology, University of LausanneLausanne, Switzerland.
University of Lausanne · CHSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance has become a major health issue. Nosocomial infections and the prevalence of resistant pathogenic bacterial strains are rising steadily. Therefore, there is an urgent need to develop new classes of antibiotics effective on multi-resistant nosocomial pathogenic bacteria. We have previously shown that a cell-permeable peptide derived from the p120 Ras GTPase-activating protein (RasGAP), called TAT-RasGAP

Indexed as

antimicrobial peptidescell-permeable peptidesRasGAPTAT-RasGAP317−326

Identifiers

PMID28638371
PMCPMC5461357
OpenAlexW2623102370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.