Evidence map›Paper›PMID 28638227›Full record

ArticleWorld journal of gastroenterology2017

Relationship between serum adenosine deaminase levels and liver histology in autoimmune hepatitis.

Murat Torgutalp, Cumali Efe, Hakan Babaoglu, Taylan Kav

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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  8. Review
  9. Serum Adenosine Deaminase as a Useful Marker to Estimate Coronary Artery Calcification in Type 2 Diabetes Mellitus Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Murat TorgutalpMurat Torgutalp, Cumali Efe, Hakan Babaoglu, Taylan Kav, Department of Gastroenterology, Hacettepe University School of Medicine, 06100 Ankara, Turkey.
Cumali EfeMurat Torgutalp, Cumali Efe, Hakan Babaoglu, Taylan Kav, Department of Gastroenterology, Hacettepe University School of Medicine, 06100 Ankara, Turkey.
Hakan BabaogluMurat Torgutalp, Cumali Efe, Hakan Babaoglu, Taylan Kav, Department of Gastroenterology, Hacettepe University School of Medicine, 06100 Ankara, Turkey.
Taylan KavMurat Torgutalp, Cumali Efe, Hakan Babaoglu, Taylan Kav, Department of Gastroenterology, Hacettepe University School of Medicine, 06100 Ankara, Turkey.
Hacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the relationship between serum adenosine deaminase (ADA) levels and histological features in patients with autoimmune hepatitis (AIH).

methodsA total of 80 subjects (52 AIH cases and 28 healthy controls) were included in the study. Patients were diagnosed according to the simplified criteria suggested by the International Autoimmune Hepatitis Group. All of the cases had been diagnosed with AIH between 2010-2015 at Hacettepe University, Department of Gastroenterology. Serum blood samples were collected and stored at -80 °C until the biochemical estimation of ADA activity. The diagnosis of patients was confirmed by liver biopsy. Serum ADA > 20 U/L was considered to be high level.

resultsMean serum ADA levels were significantly higher in AIH patients than those in healthy controls (25.4 ± 9.6 U/L

conclusionBecause of the positive correlation with inflammatory activity, serum ADA level may be a potential biomarker for predicting or monitoring histological activity in patients with AIH.

Indexed as

Adenosine DeaminaseAdultBiomarkersBiopsyCase-Control StudiesClinical Enzyme TestsFemaleHepatitis, AutoimmuneHumansLiverLiver Function TestsMaleMiddle AgedRetrospective StudiesROC CurveAdenosine DeaminaseBiomarkersAdenosine deaminaseAutoimmune hepatitisLiver biopsyNon-invasive method

Identifiers

PMID28638227
PMCPMC5467073
OpenAlexW2621445133

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.