Evidence map›Paper›PMID 28638225›Full record

ArticleWorld journal of gastroenterology2017

Sodium selenite ameliorates dextran sulfate sodium-induced chronic colitis in mice by decreasing Th1, Th17, and γδT and increasing CD4(+)CD25(+) regulatory T-cell responses.

Li-Xuan Sang, Bing Chang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Physiological Benefits of Novel Selenium Delivery via Nanoparticles.International journal of molecular sciences · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Selenium-EnrichedFrontiers in medicine · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Li-Xuan SangLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Bing ChangLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Jun-Feng ZhuLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Fang-Li YangLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Yan LiLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Xue-Feng JiangLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Da-Nan WangLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Chang-Long LuLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Xun SunLi-Xuan Sang, Jun-Feng Zhu, Fang-Li Yang, Yan Li, Xue-Feng Jiang, Da-Nan Wang, Chang-Long Lu, Xun Sun, Department of Immunology, China Medical University, Shenyang 110122, Liaoning Province, China.
Heritage Christian University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the effect of sodium selenite on the severity of dextran sulfate sodium (DSS)-induced colitis in C57BL/6 mice.

methodsMice were randomly divided into four groups (

resultsSe significantly ameliorated the symptoms of colitis and histological injury (

conclusionThese results suggest that Se protects against DSS-induced chronic colitis perhaps by increasing the number of CD4(+)CD25(+) Tregs that suppress the secretion of proinflammatory cytokines and populations of Th1, Th17, and γδT cells.

Indexed as

AnimalsAntioxidantsChronic DiseaseColitisColonCytokinesDextran SulfateDisease Models, AnimalFlow CytometryHumansIntestinal MucosaIntraepithelial LymphocytesMaleMiceMice, Inbred C57BLSodium SeleniteAntioxidantsCytokinesDextran SulfateSodium SeleniteTrace ElementsChronic colitisDextran sulfate sodiumSodium selenite

Identifiers

PMID28638225
PMCPMC5467071
OpenAlexW2623427319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.