ArticleShanghai archives of psychiatry2016
Eye Movement Indices in the Study of Depressive Disorder.
Article in Shanghai archives of psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Identifying an oculomotor phenotype for adolescent depression with an interleaved pro- and anti-saccade task.Frontiers in psychiatry · 2026Article
- Oculomotor behaviors in youth with an eating disorder: findings from a video-based eye tracking task.Journal of eating disorders · 2024Article
- Effect of eccentric fixation on the steady-state pattern electroretinogram.Documenta ophthalmologica. Advances in ophthalmology · 2024Article
- Diagnosing and tracking depression based on eye movement in response to virtual reality.Frontiers in psychiatry · 2024Article
- Differential eye movement features between Alzheimer's disease patients with and without depressive symptoms.Aging clinical and experimental research · 2023Article
- Eye-tracking in adult depression: protocol for a systematic review and meta-analysis.BMJ open · 2023Article
- Depression detection using virtual avatar communication and eye tracking.Journal of eye movement research · 2023Article
- Depression and Cognitive Impairment: Current Understanding of Its Neurobiology and Diagnosis.Neuropsychiatric disease and treatment · 2022Review
- Perception Exploration on Robustness Syndromes With Pre-processing Entities Using Machine Learning Algorithm.Frontiers in public health · 2022Article
- Contribution of Eye-Tracking to Study Cognitive Impairments Among Clinical Populations.Frontiers in psychology · 2021Article
- AI-Based Prediction and Prevention of Psychological and Behavioral Changes in Ex-COVID-19 Patients.Frontiers in psychology · 2021Review
- Eye Movement Abnormalities in Major Depressive Disorder.Frontiers in psychiatry · 2021Article
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8 authors.
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Abstract
backgroundImpaired cognition is one of the most common core symptoms of depressive disorder. Eye movement testing mainly reflects patients' cognitive functions, such as cognition, memory, attention, recognition, and recall. This type of testing has great potential to improve theories related to cognitive functioning in depressive episodes as well as potential in its clinical application.
aimsThis study investigated whether eye movement indices of patients with unmedicated depressive disorder were abnormal or not, as well as the relationship between these indices and mental symptoms.
methodsSixty patients with depressive disorder and sixty healthy controls (who were matched by gender, age and years of education) were recruited, and completed eye movement tests including three tasks: fixation task, saccade task and free-view task. The EyeLink desktop eye tracking system was employed to collect eye movement information, and analyze the eye movement indices of the three tasks between the two groups.
results(1) In the fixation task, compared to healthy controls, patients with depressive disorder showed more fixations, shorter fixation durations, more saccades and longer saccadic lengths; (2) In the saccade task, patients with depressive disorder showed longer anti-saccade latencies and smaller anti-saccade peak velocities; (3) In the free-view task, patients with depressive disorder showed fewer saccades and longer mean fixation durations; (4) Correlation analysis showed that there was a negative correlation between the pro-saccade amplitude and anxiety symptoms, and a positive correlation between the anti-saccade latency and anxiety symptoms. The depression symptoms were negatively correlated with fixation times, saccades, and saccadic paths respectively in the free-view task; while the mean fixation duration and depression symptoms showed a positive correlation.
conclusionCompared to healthy controls, patients with depressive disorder showed significantly abnormal eye movement indices. In addition patients' anxiety and depression symptoms and eye movement indices were correlated. The pathological meaning of these phenomena deserve further exploration.
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