Evidence map›Paper›PMID 28638138›Full record

ArticleScientific reports2017

Immune regulation by oral tolerance induces alternate activation of macrophages and reduces markers of plaque destabilization in Apob

Lakshmi Narasimha Thota, Thiruvelselvan Ponnusamy, Sheena Philip, Xinjie Lu, Lakshmi Mundkur

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Immune cell-mediated features of atherosclerosis.Frontiers in cardiovascular medicine · 2024
    Review
  3. Article
  4. Article
  5. Biomarkers in oral immunotherapy.Journal of Zhejiang University. Science. B
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lakshmi Narasimha ThotaResearch Scholar, Manipal University, (Madhav Nagar, Manipal) at Molecular Immunology Unit Thrombosis Research Institute, Bangalore, India.
Thiruvelselvan PonnusamyResearch Scholar, Manipal University, (Madhav Nagar, Manipal) at Molecular Immunology Unit Thrombosis Research Institute, Bangalore, India.
Sheena PhilipMolecular Immunology unit, Thrombosis Research Institute, Bangalore, India.
Xinjie LuMolecular Immunology unit, Thrombosis Research Institute, London, UK.
Lakshmi MundkurMolecular Immunology unit, Thrombosis Research Institute, Bangalore, India. lakshmi.mundkur@triindia.org.in.ORCID 0000-0003-2928-1726
Manipal Academy of Higher Education · INThrombosis Research Institute · INThrombosis Research Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is the leading cause for cardiovascular mortality. We determined the effect of multi-antigenic construct expressing three peptides AHC (ApoB100, HSP60 and outer membrane protein of chlamydia pneumonia) in stabilizing advanced atherosclerosis in Apob

Indexed as

AnimalsAortaApolipoprotein B-100AtherosclerosisBacterial Outer Membrane ProteinsCell ProliferationChaperonin 60Chlamydophila pneumoniaeCTLA-4 AntigenDiet, High-FatForkhead Transcription FactorsGene Expression RegulationHumansMacrophagesMatrix Metalloproteinase 9MiceApolipoprotein B-100Bacterial Outer Membrane ProteinsChaperonin 60CTLA-4 AntigenCtla4 protein, mouseForkhead Transcription FactorsFoxp3 protein, mouseMatrix Metalloproteinase 9Mmp9 protein, mousePeptidesThromboplastinTransforming Growth Factor beta

Identifiers

PMID28638138
PMCPMC5479867
OpenAlexW2624689231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.