Evidence map›Paper›PMID 28638068›Full record

ArticleScientific reports2017

Microbiota-derived butyrate suppresses group 3 innate lymphoid cells in terminal ileal Peyer's patches.

Sae-Hae Kim, Byeol-Hee Cho, Hiroshi Kiyono, Yong-Suk Jang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 81 citations in OpenAlex.

  1. Vancomycin Protects Against Lung Injury and Promotes Butyrate Metabolism.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
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  4. Article
  5. Regulation of innate lymphoid cell by microbial metabolites.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
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  7. Review
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  10. Article
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  16. ILC3: a case of conflicted identity.Frontiers in immunology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Sae-Hae KimDepartment of Molecular Biology and Institute for Molecular Biology and Genetics, Chonbuk National University, Jeonju, 54896, Korea.
Byeol-Hee ChoDepartment of Bioactive Material Sciences and Research Center of Bioactive Materials, Chonbuk National University, Jeonju, 54896, Korea.
Hiroshi KiyonoDivision of Mucosal Immunology and International Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
Yong-Suk JangDepartment of Molecular Biology and Institute for Molecular Biology and Genetics, Chonbuk National University, Jeonju, 54896, Korea. yongsuk@jbnu.ac.kr.
Jeonbuk National University · KRThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regional specialization of intestinal immune cells is affected by the longitudinal heterogeneity of environmental factors. Although the distribution of group 3 innate lymphoid cells (ILC3s) is well characterized in the lamina propria, it is poorly defined in Peyer's patches (PPs) along the intestine. Given that PP ILC3s are closely associated with mucosal immune regulation, it is important to characterize the regulatory mechanism of ILC3s. Here, we found that terminal ileal PPs of specific pathogen-free (SPF) mice have fewer NKp46

Indexed as

Gastrointestinal MicrobiomeAnimalsAntigens, LyButyratesIleumJejunumLymphocytesMice, Inbred BALB CMice, Inbred C57BLNatural Cytotoxicity Triggering Receptor 1Peyer's PatchesAntigens, LyButyratesNatural Cytotoxicity Triggering Receptor 1Ncr1 protein, mouse

Identifiers

PMID28638068
PMCPMC5479798
OpenAlexW2626760843

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.