Evidence map›Paper›PMID 28637875›Full record

ArticleThe Journal of biological chemistry2017

Coupled feedback loops control the stimulus-dependent dynamics of the yeast transcription factor Msn2.

Yanfei Jiang, Zohreh AkhavanAghdam, Lev S Tsimring, Nan Hao

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yanfei JiangSection of Molecular Biology, Division of Biological Sciences, La Jolla, California 92093.
Zohreh AkhavanAghdamSection of Molecular Biology, Division of Biological Sciences, La Jolla, California 92093.
Lev S TsimringBioCircuits Institute, University of California San Diego, La Jolla, California 92093.
Nan HaoSection of Molecular Biology, Division of Biological Sciences, La Jolla, California 92093; BioCircuits Institute, University of California San Diego, La Jolla, California 92093. Electronic address: nhao@ucsd.edu.

Funding

GENETIC MECHANISMS AND REGULATIONT32GM007240 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMPTON, RANDOLPH Y. · 1985 to 2019
$23.8M
Dynamically compartmentalized control of gene expression by messenger ribonucleoprotein granulesR01GM111458 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAO, NAN · 2014 to 2022
$3.4M
NIGMS NIH HHS R01 GM111458NIGMS NIH HHS T32 GM007240
6 · The paper itself

Abstract

Information about environmental stimuli often can be encoded by the dynamics of signaling molecules or transcription factors. In the yeast

Indexed as

Feedback, PhysiologicalDNA-Binding ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsDNA-Binding ProteinsMSN2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsAMP-activated kinase (AMPK)cell signalingcomputer modelingfeedback regulationprotein kinase A (PKA)signaling circuitssingle-cell imaging analysissystems biology

Identifiers

PMID28637875
PMCPMC5535011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.