Evidence map›Paper›PMID 28637872›Full record

ArticleThe Journal of biological chemistry2017

Hydrogen sulfide modulates eukaryotic translation initiation factor 2α (eIF2α) phosphorylation status in the integrated stress-response pathway.

Vinita Yadav, Xing-Huang Gao, Belinda Willard, Maria Hatzoglou, Ruma Banerjee, Omer Kabil

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Power and poison: The intersections of HThe Journal of biological chemistry · 2025
    Review
  4. Article
  5. Review
  6. Impact of Reactive Sulfur Species onAntioxidants (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Hydrogen Sulfide Oxidation by Sulfide Quinone Oxidoreductase.Chembiochem : a European journal of chemical biology · 2021
    Review
  12. Role of hydrogen sulfide donors in cancer development and progression.International journal of biological sciences · 2021
    Review
  13. Article
  14. HInflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Vinita YadavFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109.
Xing-Huang Gaothe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and.
Belinda Willardthe Proteomics and Metabolomics Laboratory, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106.
Maria Hatzoglouthe Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio 44106, and.
Ruma BanerjeeFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109.
Omer KabilFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109, omerk@umich.edu.
University of Michigan–Ann Arbor · USCase Western Reserve University · USCleveland Clinic Lerner College of Medicine · US

Funding

Regulation of Gene Expression During StressR01DK053307 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI HATZOGLOU, MARIA · 1998 to 2021
$9.6M
Translational Control by NutrientsR01DK060596 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI MARIA HATZOGLOU · 2002 to 2026
$6.3M
Transsulfuration and HyperhomocysteinemiaR01HL058984 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI BANERJEE, RUMA V · 1997 to 2020
$6.0M
Translational Control by Osmotically Active SolutesR37DK060596 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI HATZOGLOU, MARIA · 2011 to 2020
$5.3M
Enzymology of Sulfide OxidationR01GM112455 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BANERJEE, RUMA V · 2014 to 2017
$1.2M
NHLBI NIH HHS R01 HL058984NIDDK NIH HHS R01 DK053307NIDDK NIH HHS R01 DK060596NIDDK NIH HHS R37 DK060596NIGMS NIH HHS R01 GM112455
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Endoplasmic Reticulum StressActivating Transcription Factor 4AllostasisAmino Acid SubstitutionAnimalsCell LineCells, CulturedCell SurvivalCysteineEukaryotic Initiation Factor-2GasotransmittersGene Expression RegulationHumansHydrogen SulfideMiceMice, KnockoutActivating Transcription Factor 4Atf4 protein, mouseCysteineEukaryotic Initiation Factor-2GasotransmittersHydrogen SulfidePPP1CA protein, humanProtein Phosphatase 1Recombinant Proteinscytoprotectioneukaryotic initiation factor 2 (eIF2)hydrogen sulfideintegrated stress responsephosphoprotein phosphatase 1 (PP1)protein persulfidationsignalingstress responsesulfhydration

Identifiers

PMID28637872
PMCPMC5555178
OpenAlexW2639434630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.