Evidence map›Paper›PMID 28637815›Full record

ArticleJournal of neurophysiology2017

The proinflammatory cytokine tumor necrosis factor-α excites subfornical organ neurons.

Nick J Simpson, Alastair V Ferguson

Open access · greenAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Neuroimmune interactions in cardiovascular homeostasis and disease.American journal of physiology. Cell physiology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Neuronomodulation of Excitable Neurons.Neuroscience bulletin · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Anatomical Organization of the Rat Subfornical Organ.Frontiers in cellular neuroscience · 2021
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nick J SimpsonDepartment of Biomedical and Molecular Sciences and Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.
Alastair V FergusonDepartment of Biomedical and Molecular Sciences and Centre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada avf@queensu.ca.ORCID 0000-0003-1261-0036
Queen's University · CA

Funding

CIHR
6 · The paper itself

Abstract

Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine implicated in cardiovascular and autonomic regulation via actions in the central nervous system. TNF-α

Indexed as

Action PotentialsAnimalsCells, CulturedMaleNeuronsPotassium ChannelsRatsRats, Sprague-DawleySodium ChannelsSubfornical OrganTumor Necrosis Factor-alphaPotassium ChannelsSodium ChannelsTumor Necrosis Factor-alphaangiotensin IIinflammationpatch-clamp electrophysiologysubfornical organtumor necrosis factor-α

Identifiers

PMID28637815
PMCPMC5596133
OpenAlexW2682725689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.