ReviewCirculation. Cardiovascular imaging2017
Sudden Cardiac Death Substrate Imaged by Magnetic Resonance Imaging: From Investigational Tool to Clinical Applications.
Review in Circulation. Cardiovascular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01076660 (Left Ventricular Structural Predictors of Sudden Cardiac Death [Substudy of), which is not on this map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Left Ventricular Structural Predictors of Sudden Cardiac Death [Substudy of: Functional Energetics and Imaging for Phenotypic Characterization of Patients at Risk for Sudden Cardiac Death, See Also NCT000181233]
Who cites it
43 citing papers in PubMed.
- Late Gadolinium Enhancement Entropy as a Novel Imaging Biomarker of Myocardial Tissue Heterogeneity-A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2026Review
- Fibrosis Entropy Is Associated With Life-Threatening Arrhythmia in Nonischemic Cardiomyopathy.Journal of the American Heart Association · 2025Observational
- Diagnostic usefulness and limitation of cardiac magnetic resonance for identifying myocardial damage in survivors of cardiac arrest in midtown.World journal of radiology · 2025Article
- Diagnostic value and clinical impact of cardiac magnetic resonance imaging in patients after sudden cardiac arrest: a retrospective study.Open heart · 2025Article
- Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- Prediction of sudden cardiac death using artificial intelligence: Current status and future directions.Heart rhythm · 2025Review
- Precision prediction of heart failure events in patients with dilated cardiomyopathy and mildly reduced ejection fraction using multi-parametric cardiovascular magnetic resonance.European journal of heart failure · 2024Observational
- Left ventricular fibrosis in arrhythmic mitral valve prolapse: quantification and comparison of semi-automated techniques assessed by cardiac magnetic resonance.The international journal of cardiovascular imaging · 2024Article
- Association Between Left Ventricular Scar and Ventricular Ectopy in People Living With and Without HIV.JACC. Advances · 2023Article
- The Role of Cardiovascular Magnetic Resonance Imaging in Patients with Cardiac Arrhythmias.Reviews in cardiovascular medicine · 2023Review
- Late gadolinium enhancement entropy as a new measure of myocardial tissue heterogeneity for prediction of adverse cardiac events in patients with hypertrophic cardiomyopathy.Insights into imaging · 2023Article
- Parametric mapping by cardiovascular magnetic resonance imaging in sudden cardiac arrest survivors.The international journal of cardiovascular imaging · 2023Article
- Early recurrence of myocarditis with atrioventricular block while wearing a wearable cardioverter-defibrillator after fulminant myocarditis: A case report.HeartRhythm case reports · 2023Article
- T1 Map-Based Radiomics for Prediction of Left Ventricular Reverse Remodeling in Patients With Nonischemic Dilated Cardiomyopathy.Korean journal of radiology · 2023Article
- Myocardial Tissue Characterization to Predict Ventricular Arrhythmic Risk: Road Well-Traveled But So Far to Go.JACC. Cardiovascular imaging · 2023Article
- Article
- From evidence-based medicine to digital twin technology for predicting ventricular tachycardia in ischaemic cardiomyopathy.Journal of the Royal Society, Interface · 2022Article
- The Association of Clustered Ventricular Arrhythmia and Cycle Length With Scar Burden in Cardiomyopathy.JACC. Clinical electrophysiology · 2022Article
- Association of left ventricular tissue heterogeneity and intramyocardial fat on computed tomography with ventricular arrhythmias in ischemic cardiomyopathy.Heart rhythm O2 · 2022Article
- More Than Meets the Eye: Cardiac Magnetic Resonance Image Entropy and Ventricular Arrhythmia Risk Prediction.JACC. Cardiovascular imaging · 2022Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Sudden cardiac death (SCD) is a devastating event afflicting 350 000 Americans annually despite the availability of life-saving preventive therapy, the implantable cardioverter defibrillator. SCD prevention strategies are hampered by over-reliance on global left ventricular ejection fraction <35% as the most important criterion to determine implantable cardioverter defibrillator candidacy. Annually in the United States alone, this results in ≈130 000 implantable cardioverter defibrillator placements at a cost of >$3 billion but only a 5% incidence per year of appropriate firings. This approach further fails to identify individuals who experience the majority, as many as 80%, of SCD events, which occur in the setting of more preserved left ventricular ejection fraction. Better risk stratification is needed to improve care and should be guided by direct pathophysiologic markers of arrhythmic substrate, such as specific left ventricular structural abnormalities. There is an increasing body of literature to support the prognostic value of cardiac magnetic resonance imaging with late gadolinium enhancement in phenotyping the left ventricular to identify those at highest risk for SCD. Cardiac magnetic resonance has unparalleled tissue characterization ability and provides exquisite detail about myocardial structure and composition, abnormalities of which form the direct, pathophysiologic substrate for SCD. Here, we review the evolution and the current state of cardiac magnetic resonance for imaging the arrhythmic substrate, both as a research tool and for clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.