Evidence map›Paper›PMID 28637805›Full record

ArticleClinical and vaccine immunology : CVI2017

Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies.

Míriam A da Silva, Thiago R Converso, Viviane M Gonçalves, Luciana C C Leite, Martha M Tanizaki, Giovana C Barazzone

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Non-capsular based immunization approaches to preventFrontiers in cellular and infection microbiology · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Míriam A da SilvaLaboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil.
Thiago R ConversoLaboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil.
Viviane M GonçalvesLaboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil.
Luciana C C LeiteLaboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil.
Martha M TanizakiLaboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil.
Giovana C BarazzoneLaboratório Especial de Desenvolvimento de Vacinas, Instituto Butantan, São Paulo, Brazil giovana.barazzone@butantan.gov.br.ORCID http://orcid.org/0000-0001-8601-8452
Instituto Butantan · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current pneumococcal vaccines are composed of bacterial polysaccharides as antigens, plain or conjugated to carrier proteins. While efficacious against vaccine serotypes, epidemiologic data show an increasing incidence of infections caused by nonvaccine serotypes of

Indexed as

AnimalsAntibodies, BacterialBacterial ProteinsCross ReactionsImmunoglobulin GMiceMice, Inbred BALB CPneumococcal InfectionsPneumococcal VaccinesPolysaccharides, BacterialSerogroupStreptococcus pneumoniaeVaccinationVaccines, ConjugateAntibodies, BacterialBacterial ProteinsImmunoglobulin Gpneumococcal surface protein APneumococcal VaccinesPolysaccharides, BacterialVaccines, Conjugateconjugate vaccinecross-reactivitypneumococcusPneumococcusPspA

Identifiers

PMID28637805
PMCPMC5583475
OpenAlexW2648278811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.