Evidence map›Paper›PMID 28637804›Full record

ArticleClinical and vaccine immunology : CVI2017

Bioactive Immune Components of Anti-Diarrheagenic Enterotoxigenic Escherichia coli Hyperimmune Bovine Colostrum Products.

Khandra T Sears, Sharon M Tennant, Mardi K Reymann, Raphael Simon, Nicky Konstantopoulos, William C Blackwelder, Eileen M Barry, Marcela F Pasetti

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. EnterotoxigenicGut microbes
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Khandra T SearsCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Sharon M TennantCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Mardi K ReymannCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Raphael SimonCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Nicky KonstantopoulosImmuron, Blackburn North, Victoria, Australia.
William C BlackwelderCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Eileen M BarryCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Marcela F PasettiCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA mpasetti@som.umaryland.edu.
University of Maryland, Baltimore · US

Funding

Shigella Live Vector-Based Multivalent VaccineU19AI109776 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI LEVINE, MYRON MAX · 2014 to 2018
$25.4M
NIAID NIH HHS U19 AI109776
6 · The paper itself

Abstract

Diarrhea is a common illness among travelers to resource-limited countries, the most prevalent attributable agent being enterotoxigenic

Indexed as

AnimalsAntibodies, BacterialCattleColostrumCytokinesDiarrheaEnterotoxigenic Escherichia coliEnterotoxinsEscherichia coli InfectionsEscherichia coli ProteinsFemaleFimbriae ProteinsHumansImmunoglobulin AImmunoglobulin GImmunologic FactorsAntibodies, BacterialCytokinesEnterotoxinsEscherichia coli ProteinsFimbriae ProteinsImmunoglobulin AImmunoglobulin GImmunologic FactorsIntercellular Signaling Peptides and ProteinsLactoferrinbactericidal activityenterotoxigenic E. colifunctional antibodieshyperimmune colostrum

Identifiers

PMID28637804
PMCPMC5583472
OpenAlexW2627464039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.